#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3385093	Binding	Inhibition of IDH1 R132H mutant (unknown origin) assessed as inhibition of [3C]2-hydroxyglutarate formation after 45 mins by LC-MS biochemical assay	Homo sapiens	4	ALA3352118	single protein format	Scientific Literature
2.	ALA3385094	Binding	Inhibition of IDH1 R132H mutant (unknown origin) using a-ketoglutarate as substrate by fluorescence biochemical assay	Homo sapiens	4	ALA3352118	single protein format	Scientific Literature
3.	ALA4390243	Binding	Inhibition of N-terminal 6-His-tagged wild type IDH1 (unknown origin) expressed in Escherichia coli BL21 cells using alpha-KG as substrate in presence of NADPH incubated for 40 mins by fluorescence assay	Homo sapiens	16	ALA4387756	cell-based format	Scientific Literature
4.	ALA4390244	Binding	Inhibition of N-terminal 6-His-tagged IDH1 R132C mutant (unknown origin) expressed in Escherichia coli BL21 cells using alpha-KG as substrate in presence of NADPH incubated for 40 mins by fluorescence assay	Homo sapiens	16	ALA4387756	cell-based format	Scientific Literature
5.	ALA4390245	Binding	Inhibition of N-terminal 6-His-tagged IDH1 R132H mutant (unknown origin) expressed in Escherichia coli BL21 cells using alpha-KG as substrate in presence of NADPH incubated for 40 mins by fluorescence assay	Homo sapiens	17	ALA4387756	cell-based format	Scientific Literature
6.	ALA4390246	Binding	Binding affinity to N-terminal 6-His-tagged wild type IDH1 (unknown origin) expressed in BL21 cells assessed as equilibrium dissociation constant by SPR assay	Homo sapiens	1	ALA4387756	cell-based format	Scientific Literature
7.	ALA4390247	Binding	Binding affinity to N-terminal 6-His-tagged IDH1 R132C mutant (unknown origin) expressed in BL21 cells assessed as equilibrium dissociation constant by SPR assay	Homo sapiens	1	ALA4387756	cell-based format	Scientific Literature
8.	ALA4390248	Binding	Binding affinity to N-terminal 6-His-tagged IDH1 R132H mutant (unknown origin) expressed in BL21 cells assessed as equilibrium dissociation constant by SPR assay	Homo sapiens	1	ALA4387756	cell-based format	Scientific Literature
9.	ALA4390249	Binding	Inhibition of IDH1 R132H mutant in human HT1080 cells assessed as reduction in 2-HG levels after 48 hrs by LC-MS/MS analysis	Homo sapiens	1	ALA4387756	cell-based format	Scientific Literature
10.	ALA4390253	Binding	Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as induction of differentiation by measuring decrease in SOX2 mRNA expression at 1 umol/L after 6 days by qRT-PCR analysis	Homo sapiens	1	ALA4387756	cell-based format	Scientific Literature
11.	ALA4390254	Binding	Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as induction of differentiation by measuring increase in GFAP mRNA expression at 1 umol/L after 6 days by qRT-PCR analysis	Homo sapiens	1	ALA4387756	cell-based format	Scientific Literature
12.	ALA4390255	Binding	Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as induction of differentiation by measuring increase in GFAP protein expression after at 0.125 to 1 umol/L 6 days by Western blot analysis	Homo sapiens	1	ALA4387756	cell-based format	Scientific Literature
13.	ALA3388443	Binding	Inhibition of human IDH1 R132H mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumption	Homo sapiens	61	ALA3351758	assay format	Scientific Literature
14.	ALA3388444	Binding	Inhibition of wild type human IDH1 expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumption	Homo sapiens	12	ALA3351758	assay format	Scientific Literature
15.	ALA3389006	Binding	Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumption	Homo sapiens	12	ALA3351758	assay format	Scientific Literature
16.	ALA3389009	Binding	Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in D2HG production incubated for 48 hrs by HPLC-MS method	Homo sapiens	12	ALA3351758	cell-based format	Scientific Literature
17.	ALA1964082	Functional	PUBCHEM_BIOASSAY: qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): Confirmation of Cherrypicks. (Class of assay: confirmatory)		712	ALA1201862	assay format	PubChem BioAssays
18.	ALA1963857	Functional	PUBCHEM_BIOASSAY: qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): Cherrypicks in WT IDH1. (Class of assay: confirmatory)		192	ALA1201862	assay format	PubChem BioAssays
19.	ALA1963873	Functional	PUBCHEM_BIOASSAY: qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): Cherrypicks Autofluorescence Interference. (Class of assay: confirmatory)		4	ALA1201862	assay format	PubChem BioAssays
20.	ALA1964002	Functional	PUBCHEM_BIOASSAY: qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): qHTS. (Class of assay: confirmatory)		3,373	ALA1201862	assay format	PubChem BioAssays