# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1963965 | F | PUBCHEM_BIOASSAY: Dose response confirmation of uHTS RPN11 inhibitor hits in a Fluorescence Polarization assay. (Class of assay: confirmatory) | 396 | assay format | PubChem BioAssays | |||
2. | ALA4049702 | B | Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in beta5 inhibitor MG132 pretreated human HeLa cells expressing UbG76V-GFP assessed as reduction in UbG76V-GFP degradation rate by fluorescence microscopic method | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
3. | ALA4049703 | B | Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes at 200 uM using Ub4-pepOG protein substrate preincubated for 1 hr followed by substrate addition measured after 80 mins by fluorescence polarization assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4049704 | B | Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated for 1 hr followed by substrate addition measured after 80 mins by fluorescence polarization assay | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
5. | ALA4049714 | B | Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated for 1 hr followed by substrate addition measured after 80 mins in presence of Zn(cyclen)2+ by fluorescence polarization assay | Homo sapiens | 1 | cell-based format | Scientific Literature |