| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2019641 | B | Inhibition of APPBP1-mediated NEDD8 activation at 10 mM after 1.5 hrs by Western blot analysis | 2 | single protein format | Scientific Literature | |||
| 2. | ALA2328914 | B | Inhibition of NAE (unknown origin)-catalyzed NEDD8-Ubcl2 intermediate formation by densitometric analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2328915 | B | Inhibition of NAE (unknown origin) assessed as decrease in NEDD8-Ubcl2 formation | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA2328916 | B | Inhibition of NAE (unknown origin)-catalyzed transthiolation of NEDD8 from NAE to Ubc12 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA2328919 | B | Inhibition of NAE (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA2328930 | B | Inhibition of NAE (unknown origin) in presence of ATP | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4603152 | B | Inhibition of NAE-mediated neddylation in human MGC803 cells assessed as reduction in Nedd8-Cullin1 adduct formation by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4603153 | B | Inhibition of NAE (unknown origin)-mediated neddylation assessed as decrease in Nedd8-Ubcl2 adduct formation at 5 uM by Western blot analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4603154 | B | Inhibition of NAE (unknown origin)-mediated neddylation assessed as decrease in Nedd8-Ubcl2 adduct formation at 10 uM by Western blot analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4603155 | B | Inhibition of NAE-mediated neddylation in human MGC803 cells assessed as reduction in Nedd8-Ubcl2 adduct formation incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4603156 | B | Inhibition of NAE-mediated neddylation in human MGC803 cells assessed as reduction in Nedd8-Ubcl2 adduct formation at 5 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4603157 | B | Inhibition of NAE-mediated neddylation in human MGC803 cells assessed as reduction in Nedd8-Ubcl2 adduct formation at 10 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4603158 | B | Inhibition of NAE-mediated neddylation in human MGC803 cells assessed as reduction in Nedd8-Cullin3 adduct formation at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4603159 | B | Inhibition of NAE-mediated neddylation in human MGC803 cells assessed as reduction in NAE1-Nedd8 adduct formation at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4733961 | B | Inhibition of NAE (unknown origin)-mediated neddylation assessed as suppression of cullin1-Nedd8 adduct formation at 25 uM preincubated for 10 mins followed by ATP addition and measured after 30 mins by immunoblot analysis relative to control | Homo sapiens | 44 | single protein format | Scientific Literature | ||
| 16. | ALA4733963 | B | Inhibition of NAE (unknown origin)-mediated neddylation assessed as suppression of cullin1-Nedd8 adduct formation preincubated for 10 mins followed by ATP addition and measured after 30 mins by immunoblot analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 17. | ALA4733968 | B | Inhibition of NAE-mediated neddylation in human A549 cells assessed as suppression of cullin1-Nedd8 adduct formation at 12.5 to 25 uM measured after 6 to 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4733969 | B | Inhibition of NAE-mediated neddylation in human A549 cells assessed as suppression of cullin2-Nedd8 adduct formation at 12.5 to 25 uM measured after 6 to 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4733970 | B | Inhibition of NAE-mediated neddylation in human A549 cells assessed as suppression of cullin4a-Nedd8 adduct formation at 12.5 to 25 uM measured after 6 to 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4733971 | B | Inhibition of NAE-mediated neddylation in human A549 cells assessed as suppression of cullin5-Nedd8 adduct formation at 12.5 to 25 uM measured after 6 to 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!