| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2026240 | B | Inhibition of Des1 in human A549 cells assessed as formation of CerC6NBD from dhCerC6NBD at =>100 uM after 4 hrs by HPLC-FD analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA2026241 | B | Inhibition of Des1 in human HCT116 cells assessed as formation of CerC6NBD from dhCerC6NBD at =>100 uM after 4 hrs by HPLC-FD analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA2026163 | B | Inhibition of Des1 in human A549 cells assessed as formation of CerC6NBD from dhCerC6NBD after 4 hrs by HPLC-FD analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA2026164 | B | Inhibition of Des1 in human HCT116 cells assessed as formation of CerC6NBD from dhCerC6NBD after 4 hrs by HPLC-FD analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3767201 | B | Inhibition of Des1 activity in human Jurkat cells using fluorescence labeled DhCer-C6-NBD as substrate at 0.1 to 10 uM after 3 hrs by HPLC method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA3767202 | B | Inhibition of Des1 activity in human Jurkat cells using fluorescence labeled DhCer-C6-NBD as substrate at 10 uM after 3 hrs by HPLC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3767203 | B | Inhibition of Des1 activity in human Jurkat cells using fluorescence labeled DhCer-C6-NBD as substrate at 1 and 10 uM after 3 hrs by HPLC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3767358 | B | Irreversible inhibition of Des1 activity in human Jurkat cells treated with parent compound treated with fenretinide using fluorescence labeled DhCer-C6-NBD as substrate by HPLC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3767367 | B | Inhibition of Des1 (unknown origin) at 30 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA3767373 | A | Drug metabolism in human Jurkat cells assessed as DES1-mediated (2E,4E,6E,8E)-3,7-dimethyl-N-(4-oxocyclohexa-2,5-dienylidene)-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenamide formation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3767374 | A | Drug level in human Jurkat cells assessed as DES1-mediated compound oxidation treated with fenretinide | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4310700 | B | Inhibition of dihydroceramide desaturase in human MCF7 cells assessed as decrease in remaining activity at 5 to 10 uM after 24 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5226556 | B | Noncompetitive inhibition of DES1 in human HGC-27 cell lysates assessed as inhibition constant | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 14. | ALA5226562 | B | Inhibition of DES1 in human HGC-27 cell lysates | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
| 15. | ALA5226563 | B | Binding affinity to DES1 in human HGC-27 cell lysates assessed as inhibition constant | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 16. | ALA5226566 | B | Inhibition of DES1 (unknown origin) | Homo sapiens | 5 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!