| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2039382 | B | Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunit | Homo sapiens | 4 | ALA2034892 | cell-based format | Scientific Literature | |
| 2. | ALA3362642 | B | Antagonist activity at human TAS2R31 expressed in HEK-293T cells stably expressing Galpha16gust44 assessed as inhibition receptor response to saccharin by fluorescence assay | Homo sapiens | 2 | ALA3352085 | cell-based format | Scientific Literature | |
| 3. | ALA4346433 | F | Antagonist activity at recombinant human TAS2R31 transiently expressed in HEK293T co-expressing Galpha16gust44 assessed as inhibition of aristolochic acid-induced intracellular calcium level by measuring remaining activity at 25 uM by fluo-4AM dye based FLIPR assay relative to control | Homo sapiens | 2 | ALA4342523 | cell-based format | Scientific Literature | |
| 4. | ALA4417642 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 10 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.020 +/ - 0.022 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 5. | ALA4417643 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 5 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.018 +/ - 0.018 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 6. | ALA4417644 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 2.5 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.013 +/ - 0.013 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 7. | ALA4417645 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 1.25 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.014 +/ - 0.012 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 8. | ALA4417646 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 0.625 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.014 +/ - 0.005 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 9. | ALA4417647 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 0.3125 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.012 +/ - 0.001 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 10. | ALA4417648 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 0.1563 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.014 +/ - 0.006 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 11. | ALA4417649 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 0.0781 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.014 +/ - 0.003 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 12. | ALA4417650 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 0.0391 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.016 +/ - 0.011 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 13. | ALA4417651 | F | Agonist activity at full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio by Fluo-4 dye based FLIPR assay | Homo sapiens | 2 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 14. | ALA4417652 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 100 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.021 +/ - 0.012 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 15. | ALA4417653 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 50 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.018 +/ - 0.016 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 16. | ALA4417654 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.016 +/ - 0.017 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 17. | ALA4417655 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 12.5 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.016 +/ - 0.014 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 18. | ALA4417656 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 6.25 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.017 +/ - 0.009 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 19. | ALA4417657 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 3.125 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.012 +/ - 0.001 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 20. | ALA4417658 | F | Activation of full-length human TAS2R44 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 1.5625 mM by Fluo-4 dye based FLIPR assay (Rvb = 0.017 +/ - 0.008 No_unit) | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data |
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