| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2039416 | B | Inhibition of human RAD51-mediated DNA strand exchange at 10 to 100 microM using pBSK (+) gapped and linear dsDNA substrates by joint molecule formation assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA2039418 | B | Inhibition of human RAD51-mediated DNA branch migration at 10 to 100 microM using [32P]-labeled 5'-joint molecules after 8 hrs by branch migration assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2039420 | B | Inhibition of human RAD51-mediated DNA strand exchange at using pBSK (+) gapped and linear dsDNA substrates by joint molecule formation assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA2039421 | B | Inhibition of human RAD51-mediated DNA branch migration using [32P]-labeled 5'-joint molecules after 8 hrs by branch migration assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA2039422 | B | Binding affinity to human RAD51 at 50 microM by SPR method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA2039424 | B | Binding affinity to human RAD51 in absence of ATP by SPR method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA2039425 | B | Inhibition of human RAD51-ssDNA filament formation at 20 uM added to free RAD51 prior to filament formation by D-loop formation assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA2039426 | B | Inhibition of ssDNA binding to human RAD51 assessed as reduction in RAD51-90-mer ssDNA complex formation at 25 uM by EMSA method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA2039427 | B | Inhibition of human RAD51 ATPase activity at 25 uM by ATP hydrolysis assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA2039428 | B | Inhibition of human RAD51 oligomerization at 200 uM by gel filtration method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA2039429 | B | Inhibition of dsDNA binding to human RAD51-ssDNA filament assessed as reduction in coaggregation formation at 20 uM in presence of 50 mM NaCl by dsDNA coaggregation assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA2039430 | B | Inhibition of DNA binding to human RAD51 in irradiated HEK cells assessed as reduction in RAD51 foci formation at 50 uM by fluorescence microscopy relative to untreated control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA2039431 | B | Inhibition of DNA binding to human RAD51 in irradiated HEK cells assessed as RAD51 foci formation at 50 uM by fluorescence microscopy (Rvb= 72 +/- 10%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA2039432 | B | Inhibition of DNA binding to human RAD51 in irradiated HEK cells assessed as reduction in average number of RAD51 foci per nucleus at 50 uM by fluorescence microscopy relative to untreated control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA2039569 | B | Inhibition of DNA binding to human RAD51 in irradiated HEK cells assessed as reduction in RAD51 foci formation at 25 uM by fluorescence microscopy relative to untreated control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA2039570 | B | Inhibition of human RAD51 in HEK-GFP cells assessed as reduction in double-strand breaks-induced homologous recombination by chromosomally integrated DR-GFP reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA2039574 | B | Inhibition of human RAD51 in HEK-GFP cells assessed as reduction in double-strand breaks-induced homologous recombination at 20 uM by chromosomally integrated DR-GFP reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA2039576 | B | Inhibition of human RAD51-mediated DNA strand exchange at 5 to 20 uM using pBSK (+) gapped and linear dsDNA substrates by joint molecule formation assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA2039730 | B | Inhibition of human RAD51 in HEK-GFP cells assessed as reduction in double-strand breaks-induced homologous recombination at 5 to 20 uM by chromosomally integrated DR-GFP reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA2039731 | B | Inhibition of human RAD51 in HEK-GFP cells assessed as reduction in double-strand breaks-induced homologous recombination by measuring GFP fluorescence at 5 uM by chromosomally integrated DR-GFP reporter gene assay (Rvb = 3.3%) | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!