# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2039734 | B | Inhibition of RAD51 in MEF cells assessed as potentiation of 32 uM cisplatin-induced cytotoxicity at 5 uM incubated for 1 hr by clonogenic survival assay relative to untreated control | Mus musculus | 1 | ALA2034898 | cell-based format | Scientific Literature | |
2. | ALA2039735 | B | Inhibition of RAD51 in MEF cells assessed as potentiation of 1 uM MMC-induced cytotoxicity at 5 uM incubated for 1 hr by clonogenic survival assay relative to untreated control | Mus musculus | 1 | ALA2034898 | cell-based format | Scientific Literature | |
3. | ALA2039736 | B | Inhibition of RAD51 in Tp53-/- MEF cells assessed as potentiation of 32 uM cisplatin-induced cytotoxicity at 5 uM incubated for 1 hr by clonogenic survival assay relative to untreated control | Mus musculus | 1 | ALA2034898 | cell-based format | Scientific Literature | |
4. | ALA2039737 | B | Inhibition of RAD51 in Tp53-/- MEF cells assessed as potentiation of 1 uM MMC-induced cytotoxicity at 5 uM incubated for 1 hr by clonogenic survival assay relative to untreated control | Mus musculus | 1 | ALA2034898 | cell-based format | Scientific Literature | |
5. | ALA2039744 | B | Inhibition of RAD51 in MEF cells assessed as potentiation of MMC-induced cytotoxicity at 5 uM incubated for 1 hr in presence of 0.01 uM PARP1 inhibitor AZD2281 by clonogenic survival assay relative to untreated control | Mus musculus | 1 | ALA2034898 | cell-based format | Scientific Literature | |
6. | ALA2039745 | B | Inhibition of RAD51 in MEF cells assessed as potentiation of MMC-induced cytotoxicity at 5 uM incubated for 1 hr by clonogenic survival assay relative to untreated control | Mus musculus | 1 | ALA2034898 | cell-based format | Scientific Literature | |
7. | ALA3377965 | B | Inhibition of RAD51 in MEF assessed as induction of cisplatin-cell sensitivity at 5 uM relative to control | Mus musculus | 1 | ALA3352588 | single protein format | Scientific Literature | |
8. | ALA3377966 | B | Inhibition of RAD51 in MEF assessed as induction of MMC-cell sensitivity at 5 uM relative to control | Mus musculus | 1 | ALA3352588 | single protein format | Scientific Literature | |
9. | ALA3377967 | B | Inhibition of RAD51 in MEF assessed as potentiation of effect of PARP1 inhibitor olaparib on MMS-induced cytotoxicity at 5 uM relative to control | Mus musculus | 1 | ALA3352588 | single protein format | Scientific Literature | |
10. | ALA4417903 | B | Inhibition of RAD51 in BCR-ABL1-positive and BRCA1-proficient mouse 32Dcl3 cells assessed as reduction in cisplatin-induced RAD51 foci formation by AlexaFluor-594 staining based inverted fluorescence microscopy | Mus musculus | 1 | ALA4417629 | assay format | Patent Bioactivity Data | |
11. | ALA4417904 | A | Induction of RAD51 foci formation in BCR-ABL1-positive and BRCA1-proficient mouse 32Dcl3 cells by AlexaFluor-594 staining based inverted fluorescence microscopy | Mus musculus | 1 | ALA4417629 | assay format | Patent Bioactivity Data |