#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2050765	B	Ratio of Kinact to Ki for human recombinant KAT2 using L-kynurenine as substrate	Homo sapiens	14		single protein format	Scientific Literature
2.	ALA2050766	B	Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs	Homo sapiens	22		single protein format	Scientific Literature
3.	ALA1219087	B	Inhibition of human recombinant MBP-KAT2 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hr	Homo sapiens	2		cell-based format	Scientific Literature
4.	ALA1219089	B	Inhibition of KAT2 in human prefrontal cortex homogenates	Homo sapiens	1		tissue-based format	Scientific Literature
5.	ALA2329098	B	Binding affinity to C-terminal hexa histidine tagged full length human KAT2 K240S/F241G mutant harboring C-terminal thrombin cleavage site at 1 mM after 2 hrs by X-ray crystallography in presence of 2 mM PLP	Homo sapiens	4		assay format	Scientific Literature
6.	ALA2329107	B	Ratio of Kinact to Ki for human KAT2 using L-kynurenine as substrate by SpectraMax plate reader analysis	Homo sapiens	4		single protein format	Scientific Literature
7.	ALA2329109	B	Irreversible inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins over 16 hrs by SpectraMax plate reader analysis	Homo sapiens	4		single protein format	Scientific Literature
8.	ALA2329110	B	Inhibition of human KAT2 using L-kynurenine as substrate measured after 15-20 hrs by SpectraMax plate reader analysis	Homo sapiens	4		single protein format	Scientific Literature
9.	ALA2349996	B	Ratio of Kinact to Ki for inhibition of human KAT2	Homo sapiens	10		single protein format	Scientific Literature
10.	ALA2349997	B	Inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins for 16 hours by UV-visible spectra analysis	Homo sapiens	10		single protein format	Scientific Literature
11.	ALA2349998	B	Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis	Homo sapiens	10		single protein format	Scientific Literature
12.	ALA3225762	B	Ratio of Kinact to Ki for KAT2 (unknown origin)	Homo sapiens	5		single protein format	Scientific Literature
13.	ALA3225763	B	Inhibition of KAT2 (unknown origin)	Homo sapiens	5		single protein format	Scientific Literature
14.	ALA3705555	B	Inhibition Spectra Assay : Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is converted by the human KAT II (hKAT II) enzyme into KYNA.	Homo sapiens	29		single protein format	BindingDB Database
15.	ALA3706077	B	Inhibition Spectra Assay: Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is converted by the human KAT II (hKAT II) enzyme into KYNA. An inhibitor would therefore inhibit the decrease in OD370.The protocol was performed by placing the following reagents into a Costar 384 well black plate (30 uL total assay volume/well): 10 uL of 3x concentrated compound; 10 uL of 3x concentrated substrate mix (BGG (Sigma G-5009); 3 mM L-Kynurenine in 150 mM Tris Acetate (Sigma K3750); 3 mM alpha-ketoglutaric acid in 150 mM Tris Acetate (Sigma K2010); and 210 uM pyridoxal 5-phosphate (PLP) in 150 mM Tris Acetate (Sigma 9255)); and 10 uL of 3x concentrated enzyme (15 nM enzyme in 150 mM Tris Acetate with 0.3% bovine serum).Plates were sealed and incubated at 37 C. for 15-20 h before reading OD370 on a SpectraMax Plus plate reader.	Homo sapiens	29		single protein format	BindingDB Database
16.	ALA4012402	B	Inhibition of KAT2 (unknown origin) at 100 uM	Homo sapiens	1		single protein format	Scientific Literature
17.	ALA4051449	B	Inhibition of KAT2 (unknown origin)	Homo sapiens	1		single protein format	Scientific Literature
18.	ALA4628474	B	Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence assay	Homo sapiens	7		single protein format	Scientific Literature
19.	ALA4628475	B	Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation at 50 uM using L-kynurenine as substrate by fluorescence assay relative to control	Homo sapiens	3		single protein format	Scientific Literature
20.	ALA4628476	B	Binding affinity to recombinant human KAT2 assessed as change in temperature by thermal shift assay	Homo sapiens	1		single protein format	Scientific Literature