| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2050887 | B | Inhibition of mPGES-1 derived from LPS stimulated mouse RAW264.7 cells microsomal fraction using PGH2 as substrate at 1 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control | Mus musculus | 9 | cell-based format | Scientific Literature | ||
| 2. | ALA2050888 | B | Inhibition of mPGES-1 derived from LPS stimulated mouse NIH3T3 cells microsomal fraction using PGH2 as substrate at 1 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control | Mus musculus | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA2049918 | B | Inhibition of mPGES-1 derived from LPS stimulated mouse RAW264.7 cells microsomal fraction using PGH2 as substrate at 5 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA2049919 | B | Inhibition of mPGES-1 derived from LPS stimulated mouse NIH3T3 cells microsomal fraction using PGH2 as substrate at 5 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA2212750 | B | Inhibition of microsomal PGES1 in mouse RAW264.7 cells assessed as inhibition of LPS-induced PGE2 production at 10 uM incubated for 1 hr prior to LPS challenge measured after 24 hrs by enzyme immunoassay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2212751 | B | Inhibition of microsomal PGES1 in mouse RAW264.7 cells assessed as inhibition of LPS-induced PGE2 production at 1 uM incubated for 1 hr prior to LPS challenge measured after 24 hrs by enzyme immunoassay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3097607 | B | Inhibition of mPGES-1 in Swiss mouse NIH/3T3 cells using PGH2 as substrate assessed as inhibition of IL-1beta/TNFalpha-stimulated PGE2 production at 5 uM preincubated for 30 mins followed by substrate addition measured after 1 min by LC-MS/MS analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 8. | ALA3097610 | B | Inhibition of mPGES-1 in mouse RAW264.7 cells using PGH2 as substrate assessed as inhibition of LPS-stimulated PGE2 production at 5 uM preincubated for 30 mins followed by substrate addition measured after 1 min by LC-MS/MS analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 9. | ALA3772155 | B | Inhibition of microsomal PGES1 in mouse J774 cells assessed as reduction of LPS-induced PGE2 production inhibition at 100 uM by radioimmuno assay in presence of radio labelled PGE2 | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3861637 | B | Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production at 1 uM after 24 hrs relative to control | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA3861638 | B | Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production at 10 uM after 24 hrs relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3861639 | B | Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production at 3 uM after 24 hrs relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3861640 | B | Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrs | Mus musculus | 8 | cell-based format | Scientific Literature | ||
| 14. | ALA3873628 | B | Inhibition of mouse mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by substrate addition measured after 1 min | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4181302 | B | Inhibition of mouse mPGES1 at 10 uM relative to control | Mus musculus | 2 | single protein format | Scientific Literature | ||
| 16. | ALA4184954 | B | Inhibition of mPGES1 in mouse 3T3L1 cells assessed as reduction in PGE2 production at 1 to 10 ng/ml after 1 hr by ELISA | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4184955 | B | Inhibition of mPGES1 in mouse 3T3L1 cells assessed as reduction in PGE2 production at 10 ng/ml after 1 hr by ELISA relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4184956 | B | Inhibition of mPGES1 in mouse 3T3L1 cells assessed as reduction in PGE2 production after 1 hr by ELISA | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 19. | ALA4221884 | B | Inhibition of mouse mPGES1 expressed in CHO cells assessed as reduction in PGE2 production at 10 uM using PGH2 as substrate incubated for 10 mins followed by substrate addition measured for 1 min relative to control | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 20. | ALA4350356 | B | Inhibition of mouse recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate incubated for 20 mins followed by substrate addition and incubated for 60 sec by TR-FRET assay | Mus musculus | 9 | cell-based format | Scientific Literature |
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