| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2065196 | B | Binding affinity to HSPA2 in human Jurkat cells at 150 uM followed by UV irradiation for 30 mins with Wood's glass filtered medium pressure mercury arc light after cell lysis measured after denaturing wash by SDS-PAGE based pull down assay | Homo sapiens | 1 | ALA2062417 | cell-based format | Scientific Literature | |
| 2. | ALA2065255 | B | Binding affinity to HSPA2 in human Jurkat cells at 150 uM followed by UV irradiation for 30 mins with Wood's glass filtered medium pressure mercury arc light prior to cell lysis measured after denaturing wash by SDS-PAGE based pull down assay | Homo sapiens | 1 | ALA2062417 | cell-based format | Scientific Literature | |
| 3. | ALA2065263 | B | Binding affinity to HSPA2 in human Jurkat cells at 150 uM followed by UV irradiation for 30 mins with Wood's glass filtered medium pressure mercury arc light prior to cell lysis measured after denaturing wash by LC-MS/MS based pull down assay | Homo sapiens | 1 | ALA2062417 | cell-based format | Scientific Literature | |
| 4. | ALA4372103 | B | Inhibition of (2S,8S,11S,14S)-2-(4-aminobutyl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-(hydroxymethyl)-4,7,10,13,16,32-hexaoxo-36-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-19,22,25,28-tetraoxa-3,6,9,12,15,31-hexaazahexatriacontan-1-oic acid binding to human Hsp72 SBD expressed in Escherichia coli BL21 (DE3) up to 200 uM by Western blot analysis based pull down assay | Homo sapiens | 4 | ALA4371028 | assay format | Scientific Literature | |
| 5. | ALA4372108 | B | Inhibition of (2S,8S,11S,14S)-2-(4-aminobutyl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-(hydroxymethyl)-4,7,10,13,16,32-hexaoxo-36-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-19,22,25,28-tetraoxa-3,6,9,12,15,31-hexaazahexatriacontan-1-oic acid binding to human Hsp72 SBD expressed in Escherichia coli BL21 (DE3) by Western blot analysis | Homo sapiens | 4 | ALA4371028 | assay format | Scientific Literature | |
| 6. | ALA4372111 | B | Inhibition of (2S,8S,11S,14S)-2-(4-aminobutyl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-(hydroxymethyl)-4,7,10,13,16,32-hexaoxo-36-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-19,22,25,28-tetraoxa-3,6,9,12,15,31-hexaazahexatriacontan-1-oic acid binding to human Hsp72 SBD expressed in Escherichia coli BL21 (DE3) by Western blot analysis based pull down assay | Homo sapiens | 1 | ALA4371028 | assay format | Scientific Literature | |
| 7. | ALA4372112 | B | Binding affinity to human Hsp72 SBD expressed in Escherichia coli BL21 (DE3) at 100 uM by CD spectroscopy | Homo sapiens | 3 | ALA4371028 | assay format | Scientific Literature | |
| 8. | ALA4417080 | B | Covalent binding affinity to of HSP72-NBD (unknown origin) at 20 uM by intact protein mass spectrometry | Homo sapiens | 1 | ALA4414653 | single protein format | Scientific Literature | |
| 9. | ALA4417081 | B | Covalent inhibition of HSP72-NBD (unknown origin) after 0.083 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assay | Homo sapiens | 5 | ALA4414653 | single protein format | Scientific Literature | |
| 10. | ALA4417082 | B | Covalent inhibition of HSP72-NBD (unknown origin) after 19 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assay | Homo sapiens | 1 | ALA4414653 | single protein format | Scientific Literature | |
| 11. | ALA4417083 | B | Covalent inhibition of HSP72-NBD (unknown origin) after 46 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assay | Homo sapiens | 1 | ALA4414653 | single protein format | Scientific Literature | |
| 12. | ALA4417084 | B | Covalent inhibition of HSP72-NBD (unknown origin) nucleotide-derived FP probe displacement based by fluorescence polarization assay | Homo sapiens | 3 | ALA4414653 | single protein format | Scientific Literature | |
| 13. | ALA4417085 | B | Covalent inhibition of HSP72-NBD (unknown origin) after 2 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assay | Homo sapiens | 3 | ALA4414653 | single protein format | Scientific Literature | |
| 14. | ALA4417086 | B | Covalent inhibition of HSP72-NBD (unknown origin) after 24 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assay | Homo sapiens | 1 | ALA4414653 | single protein format | Scientific Literature | |
| 15. | ALA4417087 | B | Covalent inhibition of HSP72-NBD (unknown origin) after 1 hr nucleotide-derived FP probe displacement based by fluorescence polarization assay | Homo sapiens | 4 | ALA4414653 | single protein format | Scientific Literature | |
| 16. | ALA4417088 | B | Covalent inhibition of HSP72-NBD (unknown origin) after 0.33 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assay | Homo sapiens | 2 | ALA4414653 | single protein format | Scientific Literature | |
| 17. | ALA4417089 | B | Covalent inhibition of HSP72-NBD (unknown origin) assessed as Kinact/Ki ratio after 0.083 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assay | Homo sapiens | 1 | ALA4414653 | single protein format | Scientific Literature | |
| 18. | ALA4417090 | B | Covalent inhibition of HSP72-NBD (unknown origin) assessed as Kinact/Ki ratio after 19 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assay | Homo sapiens | 1 | ALA4414653 | single protein format | Scientific Literature | |
| 19. | ALA4417091 | B | Covalent inhibition of HSP72-NBD (unknown origin) assessed as Kinact/Ki ratio after 0.083 to 2 hrs nucleotide-derived FP probe displacement based by fluorescence polarization assay | Homo sapiens | 1 | ALA4414653 | single protein format | Scientific Literature | |
| 20. | ALA4417092 | B | Covalent inhibition of HSP72-NBD (unknown origin) assessed as Kinact/Ki ratio nucleotide-derived FP probe displacement based by fluorescence polarization assay | Homo sapiens | 1 | ALA4414653 | single protein format | Scientific Literature |
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