# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2077213 | Functional | TP_TRANSPORTER: uptake in OCT3-expressing HEK293 cells | 5 | ALA2074295 | cell-based format | TP-search Transporter Database | ||
2. | ALA2077362 | Functional | TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 0.2 uM) in OCT3-expressing HEK293 cells | 3 | ALA2073835 | cell-based format | TP-search Transporter Database | ||
3. | ALA2075862 | Functional | TP_TRANSPORTER: uptake in OCT3-expressing HRPE cells | 2 | ALA2073845 | cell-based format | TP-search Transporter Database | ||
4. | ALA2075863 | Functional | TP_TRANSPORTER: uptake in OCT3-expressing HEK293 cells | 2 | ALA2074492 | cell-based format | TP-search Transporter Database | ||
5. | ALA2075864 | Functional | TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HEK293 cells | 2 | ALA2074295 | cell-based format | TP-search Transporter Database | ||
6. | ALA2078549 | Functional | TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HRPE cells | 7 | ALA2073845 | cell-based format | TP-search Transporter Database | ||
7. | ALA2078181 | Functional | TP_TRANSPORTER: uptake in OCT3-expressing 293 cells | 1 | ALA2073758 | cell-based format | TP-search Transporter Database | ||
8. | ALA2078182 | Functional | TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HEK293 cells | 1 | ALA2074492 | cell-based format | TP-search Transporter Database | ||
9. | ALA2078183 | Functional | TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 0.1? uM, cimetidine: 100 uM) in OCT3-expressing HEK293 cells | 1 | ALA2074295 | cell-based format | TP-search Transporter Database | ||
10. | ALA2077954 | Functional | TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 0.25 uM) in OCT3-expressing HEK293 cells | 8 | ALA2074233 | cell-based format | TP-search Transporter Database | ||
11. | ALA2320301 | Binding | Inhibition of human OCT3-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay | Homo sapiens | 12 | ALA2311273 | cell-based format | Scientific Literature | |
12. | ALA4046327 | Binding | Inhibition of human OCT3 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting method | Homo sapiens | 9 | ALA4043181 | cell-based format | Scientific Literature | |
13. | ALA4046329 | Binding | Inhibition of OCT3 (unknown origin) | Homo sapiens | 1 | ALA4043181 | single protein format | Scientific Literature | |
14. | ALA4046331 | Binding | Competitive inhibition of human OCT3 expressed in HEK293 cells up to 25 uM in presence of varying concentration of MPP+ by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA4043181 | cell-based format | Scientific Literature | |
15. | ALA4046332 | Binding | Competitive inhibition of human OCT3 expressed in HEK293 cells up to 10 uM in presence of varying concentration of MPP+ by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA4043181 | cell-based format | Scientific Literature | |
16. | ALA4046333 | Binding | Competitive inhibition of human OCT3 expressed in HEK293 cells in presence of varying concentration of MPP+ by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA4043181 | cell-based format | Scientific Literature | |
17. | ALA4323344 | Binding | Substrate activity at human OCT3 expressed in HEK293 cells assessed as increase in compound uptake by measuring Vmax incubated for 2 mins by LC-MS/MS analysis based Michaelis-Menten plot analysis relative to control empty vector transfected cells | Homo sapiens | 3 | ALA4321821 | cell-based format | Scientific Literature | |
18. | ALA4323345 | Binding | Substrate activity at human OCT3 expressed in HEK293 cells assessed as increase in compound uptake by measuring Km incubated for 2 mins by LC-MS/MS analysis based Michaelis-Menten plot analysis relative to control empty vector transfected cells | Homo sapiens | 3 | ALA4321821 | cell-based format | Scientific Literature | |
19. | ALA4323353 | Binding | Substrate activity at human OCT3 expressed in HEK293 cells assessed as increase in compound uptake up to 200 uM incubated for 2 mins by LC-MS/MS analysis based Michaelis-Menten plot analysis relative to control empty vector transfected cells | Homo sapiens | 1 | ALA4321821 | cell-based format | Scientific Literature | |
20. | ALA4375700 | ADME | Substrate activity at OCT3 in human Caco2 cells assessed as protein-mediated drug uptake at 0.5 mM measured after 10 mins in absence of OCT1 substrate metformin by UPLC-MS/MS analysis | Homo sapiens | 2 | ALA4373712 | cell-based format | Scientific Literature |