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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1614319 | Functional | PUBCHEM_BIOASSAY: Confirmation of Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) [Related pubchem assays: 1768, 2076, 1766 ] | Homo sapiens | 219 | ALA1201862 | assay format | PubChem BioAssays | |
2. | ALA1614257 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) | Homo sapiens | 37,649 | ALA1201862 | assay format | PubChem BioAssays | |
3. | ALA1614531 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) | Homo sapiens | 9,451 | ALA1201862 | assay format | PubChem BioAssays | |
4. | ALA1613809 | Functional | PUBCHEM_BIOASSAY: Confirmation of Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) [Related pubchem assays: 1768, 1766, 2076 ] | Homo sapiens | 89 | ALA1201862 | assay format | PubChem BioAssays | |
5. | ALA1613988 | Functional | PUBCHEM_BIOASSAY: Confirmation of Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Confirmation in an HTRF (commercial TR-FRET) Assay using His-tagged menin and biotin-labeled MLL peptide. (Class of assay: confirmatory) [Related pubchem assays: 1768, 2076, 1766 ] | Homo sapiens | 95 | ALA1201862 | assay format | PubChem BioAssays | |
6. | ALA4366900 | Binding | Inhibition of Menin-MLL protein-protein interaction in human MV411 cells assessed as reduction in Hoxa9 mRNA expression at 30 to 300 nM after 48 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4364283 | cell-based format | Scientific Literature | |
7. | ALA4366901 | Binding | Inhibition of Menin-MLL protein-protein interaction in human MOLM13 cells assessed as reduction in Hoxa9 mRNA expression at 100 nM to 1 uM after 48 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4364283 | cell-based format | Scientific Literature | |
8. | ALA4366902 | Binding | Inhibition of Menin-MLL protein-protein interaction in human MV411 cells assessed as reduction in MEIS1 mRNA expression at 30 to 300 nM after 48 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4364283 | cell-based format | Scientific Literature | |
9. | ALA4366903 | Binding | Inhibition of Menin-MLL protein-protein interaction in human MOLM13 cells assessed as reduction in MEIS1 mRNA expression at 100 nM to 1 uM after 48 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4364283 | cell-based format | Scientific Literature | |
10. | ALA4370539 | Binding | Inhibition of full length human menin/FAM-tagged MLL1 (unknown origin) protein-protein interaction after 15 mins by fluorescence polarization assay | Homo sapiens | 18 | ALA4368922 | protein format | Scientific Literature | |
11. | ALA2114813 | Functional | PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding: Counterscreen HTRF assay. (Class of assay: confirmatory) | Homo sapiens | 49 | ALA1201862 | assay format | PubChem BioAssays | |
12. | ALA3587283 | Binding | Inhibition of menin-MLL1 interaction (unknown origin) incubated for 1 hr by fluorescein and Texas Red labeled MBM1 based fluorescence polarization assay | Homo sapiens | 13 | ALA3585303 | protein format | Scientific Literature | |
13. | ALA3587284 | Binding | Inhibition of menin-MLL1 interaction (unknown origin) | Homo sapiens | 2 | ALA3585303 | protein format | Scientific Literature | |
14. | ALA3757151 | Binding | Inhibition of menin-MLL (unknown origin) interaction | Homo sapiens | 1 | ALA3751840 | protein format | Scientific Literature | |
15. | ALA3782822 | Binding | Inhibition of menin-MLL interaction (unknown origin) after 1 hr by fluorescence polarization assay | Homo sapiens | 37 | ALA3779881 | protein format | Scientific Literature | |
16. | ALA4202221 | Binding | Inhibition of menin-MLL1 (unknown origin) protein-protein interaction by fluorescence polarization assay | Homo sapiens | 6 | ALA4196228 | protein format | Scientific Literature | |
17. | ALA4202224 | Binding | Inhibition of menin-MLL1 (unknown origin) protein-protein interaction by HTRF assay | Homo sapiens | 6 | ALA4196228 | protein format | Scientific Literature | |
18. | ALA4262729 | Binding | Inhibition of menin (unknown origin)-fluorescein-labeled MLL1 (unknown origin) after 1 hr by fluorescence polarization assay | Homo sapiens | 7 | ALA4261532 | protein format | Scientific Literature | |
19. | ALA4262730 | Binding | Inhibition of full length human menin-MLL1 (4 to 43 residues) (unknown origin) protein-protein interaction after 1 hr by fluorescence polarization assay | Homo sapiens | 2 | ALA4261532 | protein format | Scientific Literature | |
20. | ALA4262731 | Binding | Inhibition of menin (unknown origin)-FITC-tagged MLL1 (unknown origin) protein-protein interaction after 1 hr by fluorescence polarization assay | Homo sapiens | 8 | ALA4261532 | protein format | Scientific Literature |
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