# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3424946 | Binding | Activation of PI3K/Akt/eNOS signaling in HAEC assessed as inhibition of L5-induced p38 MAPK phosphorylation preincubated for 30 mins followed by L5 induction measured after 120 mins by Western blot analysis in presence of PI3K inhibitor wortmannin, Akt inhibitor, eNOS inhibitor L-NAME | Homo sapiens | 1 | ALA3421557 | protein format | Scientific Literature | |
2. | ALA3424948 | Binding | Inhibition of p38 MAPK in HAEC assessed as reduction of L5-induced caspase-3 activation at 2 uM preincubated for 30 mins followed by L5 induction measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3421557 | protein format | Scientific Literature | |
3. | ALA3429852 | Binding | Induction of p38 MAPK phosphorylation in human MDA-MB-231 cells at 7.5 to 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA3425411 | cell-based format | Scientific Literature | |
4. | ALA3429853 | Binding | Induction of p38 MAPK phosphorylation in human MDA-MB-231 cells at 5 to 7.5 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3425411 | cell-based format | Scientific Literature | |
5. | ALA3578501 | Binding | Competitive binding affinity to p38 in human A375 cells after 15 mins in presence of ATP analogue | Homo sapiens | 1 | ALA3576847 | cell-based format | Scientific Literature | |
6. | ALA3578955 | Binding | Inhibition of p38 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assay | Homo sapiens | 6 | ALA3576797 | protein format | Scientific Literature | |
7. | ALA3579065 | Binding | Inhibition of p38 (unknown origin) using biotinylated FL-ATF-2 as substrate at 10 uM after 1 hr by homogeneous time-resolved fluorescence assay | Homo sapiens | 1 | ALA3576797 | protein format | Scientific Literature | |
8. | ALA3610909 | Binding | Inhibition of p38 MAPK phosphorylation in human HepG2 cells at 1.56 to 25 uM by Western blot analysis | Homo sapiens | 1 | ALA3608289 | cell-based format | Scientific Literature | |
9. | ALA3610910 | Binding | Inhibition of p38 MAPK phosphorylation in human doxorubicin-resistant HepG2 cells expressing p-gp at 1.56 to 25 uM by Western blot analysis | Homo sapiens | 1 | ALA3608289 | cell-based format | Scientific Literature | |
10. | ALA3610915 | Binding | Inhibition of p38 MAPK phosphorylation in human HepG2 cells at 25 uM by Western blot analysis | Homo sapiens | 1 | ALA3608289 | cell-based format | Scientific Literature | |
11. | ALA3610916 | Binding | Inhibition of p38 MAPK phosphorylation in human doxorubicin-resistant HepG2 cells expressing p-gp at 25 uM by Western blot analysis | Homo sapiens | 1 | ALA3608289 | cell-based format | Scientific Literature | |
12. | ALA3611517 | Binding | Inhibition of p38 MAPK phosphorylation in human HepG2 cells at 1.56 to 25 uM by Western blot analysis in presence of NAC | Homo sapiens | 1 | ALA3608289 | cell-based format | Scientific Literature | |
13. | ALA3611518 | Binding | Inhibition of p38 MAPK phosphorylation in human doxorubicin-resistant HepG2 cells expressing p-gp at 1.56 to 25 uM by Western blot analysis in presence of NAC | Homo sapiens | 1 | ALA3608289 | cell-based format | Scientific Literature | |
14. | ALA3611521 | Binding | Inhibition of p38 MAPK phosphorylation in human HepG2 cells at 1.56 to 25 uM by Western blot analysis in presence of SB203580 | Homo sapiens | 1 | ALA3608289 | cell-based format | Scientific Literature | |
15. | ALA3611522 | Binding | Inhibition of p38 MAPK phosphorylation in human doxorubicin-resistant HepG2 cells expressing p-gp at 1.56 to 25 uM by Western blot analysis in presence of SB203580 | Homo sapiens | 1 | ALA3608289 | cell-based format | Scientific Literature | |
16. | ALA3611609 | Binding | Inhibition of p38 MAP kinase (unknown origin) by biochemical assay | Homo sapiens | 21 | ALA3608297 | protein format | Scientific Literature | |
17. | ALA3625103 | Binding | Inhibition of human p38 phosphorylation in human DU145 cells after 48 hrs by Western blotting | Homo sapiens | 1 | ALA3621107 | cell-based format | Scientific Literature | |
18. | ALA3627373 | Binding | Activation of p38 in human Caki1 cells assessed as suppression of urokinase type plasminogen activator expression at 250 to 1000 pM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3621165 | cell-based format | Scientific Literature | |
19. | ALA3627374 | Binding | Activation of p38 in human Caki1 cells assessed as suppression of MMP2 expression at 250 to 1000 pM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3621165 | cell-based format | Scientific Literature | |
20. | ALA3627375 | Binding | Activation of p38 in human Caki1 cells assessed as suppression of Rac1 expression at 250 to 1000 pM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3621165 | cell-based format | Scientific Literature |