# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA682640 | Binding | Percentage modulation of GABA EC20 against human GABA-A receptor alpha-5-beta-3-gamma-2 subunits expressed in Xenopus laevis oocytes | Homo sapiens | 1 | ALA1135580 | cell-based format | Scientific Literature | |
2. | ALA678598 | Binding | Binding affinity against human GABA-A receptor alpha-5-beta-3-gamma-2 subunits | Homo sapiens | 1 | ALA1149126 | protein complex format | Scientific Literature | |
3. | ALA678599 | Functional | Partial agonistic activity against GABA-A receptor alpha-5-beta-3-gamma-2 subunits | Homo sapiens | 1 | ALA1149126 | assay format | Scientific Literature | |
4. | ALA678600 | Functional | Maximum percent change compared to GABA EC20 against GABA-A alpha-5-beta-3-gamma-2 receptor | Homo sapiens | 1 | ALA1149126 | assay format | Scientific Literature | |
5. | ALA678601 | Functional | Maximum percent change compared to GABA EC20 against GABA-A alpha-5-beta-3-gamma-2 receptor | Homo sapiens | 3 | ALA1149126 | assay format | Scientific Literature | |
6. | ALA678745 | Binding | Binding affinity for human GABA-A receptor alpha-5-beta-3-gamma-2 subunits in L(tk-) cells | Homo sapiens | 62 | ALA1149126 | cell-based format | Scientific Literature | |
7. | ALA678746 | Binding | In vitro binding affinity for human GABA-A receptor alpha-5-beta-3-gamma-2 subunits expressed in L(tk-) cell membranes | Homo sapiens | 7 | ALA1146597 | cell-based format | Scientific Literature | |
8. | ALA681632 | Binding | Inhibition of [3H]Ro-151788 binding to human alpha-5-beta-3-gamma-2 GABA-A receptor expressed in L(tk-) cells | Homo sapiens | 1 | ALA1148356 | cell-based format | Scientific Literature | |
9. | ALA682904 | Binding | Percentage modulation of GABA EC20 against human GABA-A receptor alpha-5-beta-3-gamma-2 subunits expressed in Xenopus laevis oocytes | Homo sapiens | 8 | ALA1135580 | cell-based format | Scientific Literature | |
10. | ALA680324 | Functional | Effective concentration against human Alpha-5-beta-3-gamma-2 GABA-A receptor was determined | 1 | ALA1148356 | assay format | Scientific Literature | ||
11. | ALA680325 | Functional | Percentage modulation of submaximal (EC20) response to GABA-A receptor alpha-5-beta-3-gamma-2 subunits expressed in Xenopus laevis oocytes | Homo sapiens | 7 | ALA1146760 | cell-based format | Scientific Literature | |
12. | ALA680326 | Functional | Percentage modulation of submaximal (EC20) response to GABA-A receptor alpha-5-beta-3-gamma-2 subunits expressed in mouse fibroblast L(tk-) cells | Homo sapiens | 7 | ALA1146760 | cell-based format | Scientific Literature | |
13. | ALA877818 | Binding | Percentage modulation of submaximal (EC20) response to GABA in Xenopus oocytes expressing human GABA-A alpha-5-beta-3-gamma-2 subunits | Homo sapiens | 12 | ALA1149152 | cell-based format | Scientific Literature | |
14. | ALA680666 | Functional | Percent change in electrophysiological response in Xenopus oocytes expressing Alpha-5-beta-3-gamma-2 GABA-A receptor | 18 | ALA1148356 | cell-based format | Scientific Literature | ||
15. | ALA680667 | Functional | Percent change in electrophysiological response in Xenopus oocytes expressing alpha-5-beta-3-gamma-2 GABA-A receptor | Homo sapiens | 1 | ALA1148356 | cell-based format | Scientific Literature | |
16. | ALA680668 | Functional | Percent maximum change in electrophysiological response in Xenopus oocytes expressing alpha-5-beta-3-gamma-2 GABA-A receptor | Homo sapiens | 2 | ALA1148356 | cell-based format | Scientific Literature | |
17. | ALA680669 | Binding | Binding affinity towards human alpha-5-beta-3-gamma-2 GABA-A receptor using [3H]Ro-151788 expressed in L(tk-) cells | 35 | ALA1148356 | cell-based format | Scientific Literature | ||
18. | ALA680670 | Binding | In vitro inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-5-beta-3-gamma-2 subunits expressed in L(tk-)cells | Homo sapiens | 2 | ALA1147626 | cell-based format | Scientific Literature | |
19. | ALA680671 | Binding | Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-5-beta-3-gamma-2 | Homo sapiens | 1 | ALA1146760 | protein complex format | Scientific Literature | |
20. | ALA680672 | Binding | Inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-5-beta-3-gamma-2 subunits | Homo sapiens | 13 | ALA1146760 | protein complex format | Scientific Literature |