# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA682646 | B | In vitro binding affinity for human GABA-A receptor alpha-2-beta-3-gamma-2 subunits expressed in L(tk-) cell membranes | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA676830 | F | Partial agonistic activity against GABA-A receptor alpha-2-beta-3-gamma-2 subunits | Homo sapiens | 1 | assay format | Scientific Literature | ||
3. | ALA676831 | B | Efficacy against human GABA-A receptor alpha-2-beta-3-gamma-2 subunits expressed in L(tk-) cells by whole-cell patch-clamp | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA676832 | B | Efficacy relative to GABA EC20 against human GABA-A receptor alpha-2-beta-3-gamma-2 subunits expressed in Xenopus oocytes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA676833 | F | Maximum percent change compared to GABA EC20 against GABA-A alpha-2-beta-3-gamma-2 receptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
6. | ALA677001 | F | Maximum percent change compared to GABA EC20 against GABA-A alpha-2-beta-3-gamma-2 receptor | Homo sapiens | 3 | assay format | Scientific Literature | ||
7. | ALA681841 | B | Binding affinity for human GABA-A receptor alpha-2-beta-3-gamma-2 subunits in L(tk-) cells | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
8. | ALA681842 | B | Binding affinity for human GABA-A receptor alpha-2-beta-3-gamma-2 subunits in L(tk-) cells (not determined) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA681843 | B | In vitro displacement of [3H]Ro-151788 from human GABA-A receptor alpha-2-beta-3-gamma-2 subunits expressed in L(tk-) cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA681844 | B | In vitro binding affinity for human GABA-A receptor alpha-2-beta-3-gamma-2 subunits expressed in L(tk-) cell membranes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA680444 | B | Percentage modulation of submaximal (EC20) response to GABA in Xenopus oocytes expressing human GABA-A alpha-2-beta-3-gamma-2 subunits | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
12. | ALA877823 | F | Percent change in electrophysiological response in Xenopus oocytes expressing Alpha2-beta3-gamma2 GABA-A receptor | 12 | cell-based format | Scientific Literature | |||
13. | ALA680445 | F | Percent change in electrophysiological response in Xenopus oocytes expressing alpha-2-beta-3-gamma-2 GABA-A receptor | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA680446 | F | Percent maximum change in electrophysiological response in Xenopus oocytes expressing alpha-2-beta-3-gamma-2 GABA-A receptor | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA682708 | B | Binding affinity evaluated by ability to displace [3H]-Ro-15-1788 from recombinant human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 expressed in L(tk-)cells | 16 | cell-based format | Scientific Literature | |||
16. | ALA682709 | B | Binding affinity towards human gamma-aminobutyric-acid A receptor alpha-2-beta-3-gamma-2 using [3H]Ro-151788 expressed in L(tk-) cells | 36 | cell-based format | Scientific Literature | |||
17. | ALA682710 | B | In vitro inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-2-beta-3-gamma-2 subunits expressed in L(tk-)cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA682711 | B | Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-2-beta-3-gamma-2 | Homo sapiens | 14 | protein complex format | Scientific Literature | ||
19. | ALA682712 | B | Displacement of [3H]-Ro- 15-1788 from human GABA-A alpha-2-beta-3-gamma-2 receptor subunits expressed in Xenopus oocytes | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
20. | ALA682713 | B | Displacement of [3H]-Ro- 15-1788 from human GABA-A alpha-2-beta-3-gamma-2 receptor subunits expressed in Xenopus oocytes | Homo sapiens | 1 | cell-based format | Scientific Literature |