#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3607613	Binding	Interfacial poisoning activity at DNA-topoisomerase 2 (unknown origin) using catenated kDNA as substrate assessed as linear DNA formation at 1 to 100 uM after 30 mins by agarose gel electrophoresis	Homo sapiens	2	ALA3603803	protein format	Scientific Literature
2.	ALA3607614	Binding	Inhibition of DNA-topoisomerase 2 catalytic activity (unknown origin) using catenated kDNA as substrate assessed as formation of nicked circular and relaxed DNA at 1 to 100 uM after 30 mins by agarose gel electrophoresis	Homo sapiens	1	ALA3603803	protein format	Scientific Literature
3.	ALA661468	Binding	Compound was tested for DNA Topoisomerase II mediated cleavage of DNA; Each (+) indicates 1 to 2 -fold increase		2	ALA1150465	protein format	Scientific Literature
4.	ALA661469	Binding	Compound was tested for DNA Topoisomerase II mediated cleavage of DNA; Each (+) indicates 1 to 2 -fold increase		1	ALA1121863	protein format	Scientific Literature
5.	ALA662161	Binding	Compound was tested for DNA Topoisomerase II mediated cleavage of DNA; Each + indicates 2 to 4 fold increase		3	ALA1150465	protein format	Scientific Literature
6.	ALA875388	Binding	Compound was tested for DNA Topoisomerase II mediated cleavage of DNA; No increase		1	ALA1150465	protein format	Scientific Literature
7.	ALA662162	Binding	Compound was tested for DNA Topoisomerase II mediated cleavage of DNA; inactive		2	ALA1150465	protein format	Scientific Literature
8.	ALA662163	Binding	Double strand DNA breakage reflecting stabilization of DNA topoisomerase II intermediate by the compound expressed in terms of ng of DNA/unit of enzyme/mM of drug		9	ALA1126345	assay format	Scientific Literature
9.	ALA662164	Binding	Antibacterial activity against human DNA Topoisomerase II		3	ALA1134350	protein format	Scientific Literature
10.	ALA662165	Binding	Compound was evaluated for the inhibition of human DNA Topoisomerase II		2	ALA1126321	protein format	Scientific Literature
11.	ALA662166	Binding	Inhibition of human DNA Topoisomerase II	Homo sapiens	14	ALA1125392	protein format	Scientific Literature
12.	ALA662167	Binding	Evaluated for inhibitory activity against DNA topoisomerase II		9	ALA1125061	protein format	Scientific Literature
13.	ALA662168	Binding	Inhibition of DNA topoisomerase II at 100 uM.		17	ALA1125061	protein format	Scientific Literature
14.	ALA667217	Binding	Inhibitory activity for 50% on topoisomerase II isolated from Giardia lamblia	Giardia intestinalis	1	ALA1128267	protein format	Scientific Literature
15.	ALA667218	Binding	Inhibitory activity for 50% on topoisomerase II isolated from Giardia lamblia	Giardia intestinalis	6	ALA1128267	protein format	Scientific Literature
16.	ALA664230	Binding	Concentration of compound at which inhibitory activity detected against DNA topoisomerase II	Drosophila melanogaster	9	ALA1131312	protein format	Scientific Literature
17.	ALA664231	Binding	Concentration of compound at which inhibitory activity detected against DNA topoisomerase II; Not tested	Drosophila melanogaster	2	ALA1131312	protein format	Scientific Literature
18.	ALA668898	Binding	In vitro inhibitory activity against DNA topoisomerase II	Drosophila melanogaster	1	ALA1131312	protein format	Scientific Literature
19.	ALA668900	Binding	Inhibition of human DNA Topoisomerase II mediated DNA cleavage through the stabilization of transient DAN/topoisomerase II cleavage complex		22	ALA1149329	protein format	Scientific Literature
20.	ALA668901	Binding	Inhibitory activity against human DNA Topoisomerase-2, activity is expressed as relative DNA cleavage compared to Azatoxin by densitometric analysis		10	ALA1129326	protein format	Scientific Literature