# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA650909 | B | Inhibitory activity based on the inhibition of [Ca2+] mobilization induced by human SDF-1alpha stimulation through C-X-C chemokine receptor type 4 | 1 | ALA1135248 | single protein format | Scientific Literature | ||
2. | ALA650910 | B | Inhibitory activity based on the inhibition of [Ca2+] mobilization induced by human SDF-1alpha stimulation through C-X-C chemokine receptor type 4 | 1 | ALA1135248 | single protein format | Scientific Literature | ||
3. | ALA650911 | B | Binding affinity towards CXCR4 receptor | 1 | ALA1135101 | single protein format | Scientific Literature | ||
4. | ALA652951 | B | Compound was evaluated for its inhibitory activity against C-X-C chemokine receptor type 4 | 3 | ALA1133867 | single protein format | Scientific Literature | ||
5. | ALA652952 | B | Inhibitory activity against C-X-C chemokine receptor type 4 | 7 | ALA1133866 | single protein format | Scientific Literature | ||
6. | ALA652953 | B | Compound was evaluated for its inhibitory activity against C-X-C chemokine receptor type 4 | 3 | ALA1133867 | single protein format | Scientific Literature | ||
7. | ALA884098 | B | Inhibitory activity against CX3C chemokine receptor 4-specific monoclonal antibody 12G5 (mAb-12G5) binding to human chemokinin receptor CXCR4 in lymphocytic SUP-T1 cells | 10 | ALA1132406 | cell-based format | Scientific Literature | ||
8. | ALA885068 | B | Inhibitory activity based on the inhibition of [Ca2+] mobilization induced by human SDF-1alpha stimulation through CXCR4 | 4 | ALA1135248 | single protein format | Scientific Literature | ||
9. | ALA665166 | B | Inhibitory activity based on the inhibition of [Ca2+] mobilization induced by human SDF-1alpha stimulation through CXCR4; N.T. means not tested | 1 | ALA1135248 | single protein format | Scientific Literature | ||
10. | ALA665167 | B | Inhibitory activity based on the inhibition of [Ca2+] mobilization induced by human SDF-1alpha stimulation through CXCR4 | 3 | ALA1135248 | single protein format | Scientific Literature | ||
11. | ALA665168 | B | Inhibitory activity based on the inhibition of [Ca2+] mobilization induced by human SDF-1alpha stimulation through CXCR4; N.T. means not tested | 4 | ALA1135248 | single protein format | Scientific Literature | ||
12. | ALA712344 | F | Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assay | 19 | ALA1134146 | cell-based format | Scientific Literature | ||
13. | ALA710307 | F | Inhibitory concentration determined on an HIV infection model mediated by CXCR4 | 7 | ALA1134146 | assay format | Scientific Literature | ||
14. | ALA710308 | F | Inhibitory concentration determined on an HIV infection model mediated by CXCR4; Not tested | 13 | ALA1134146 | assay format | Scientific Literature | ||
15. | ALA710701 | F | Inhibition of HIV-induced cytopathogenicity in MT-4 cell | Homo sapiens | 21 | ALA1132828 | cell-based format | Scientific Literature | |
16. | ALA852821 | F | Ratio of cytotoxic concentration (CC50) in test-II to that of EC50 of compound; Not tested | Homo sapiens | 12 | ALA1132828 | assay format | Scientific Literature | |
17. | ALA874557 | B | Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 expressed in CHO cells | 8 | ALA1145173 | cell-based format | Scientific Literature | ||
18. | ALA827762 | B | Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cells | 28 | ALA1144415 | cell-based format | Scientific Literature | ||
19. | ALA832941 | B | Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cells; range = 1-10 uM | 4 | ALA1144415 | cell-based format | Scientific Literature | ||
20. | ALA869752 | F | Antagonist activity against human recombinant CXCR4 expressed in CHO cells assessed as inhibition of human SDF1-alpha-stimulated calcium mobilization | Homo sapiens | 15 | ALA1138901 | cell-based format | Scientific Literature |