# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA683724 | Functional | Inhibition of LTB4 -induced bronchoconstriction in guinea pigs following 0.1 mg/kg prior to challenge. | Cavia porcellus | 18 | ALA1151094 | organism-based format | Scientific Literature | |
2. | ALA683518 | Functional | Inhibition of LTB4 induced bronchospasm in guinea pig was determined in at 50 mg/kg i.d. | Cavia porcellus | 2 | ALA1123920 | organism-based format | Scientific Literature | |
3. | ALA684129 | Functional | In vitro inhibition of [3H]LTB4 receptor binding in guinea pig lung membrane | Cavia porcellus | 1 | ALA1126984 | cell membrane format | Scientific Literature | |
4. | ALA684131 | Functional | Inhibition of [3H]LTB4 receptor binding in guinea pig lung membrane | Cavia porcellus | 14 | ALA1126984 | cell membrane format | Scientific Literature | |
5. | ALA700858 | Functional | Inhibition of LTB4-induced human neutrophil CD11b/CD18 integrin up-regulation | Homo sapiens | 5 | ALA1126984 | assay format | Scientific Literature | |
6. | ALA700859 | Binding | Inhibition of [3H]LTB4 receptor binding in human neutrophils | Homo sapiens | 15 | ALA1126984 | protein format | Scientific Literature | |
7. | ALA700862 | Functional | Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils | 12 | ALA1130879 | assay format | Scientific Literature | ||
8. | ALA700863 | Functional | Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. | 23 | ALA1130879 | assay format | Scientific Literature | ||
9. | ALA700864 | Functional | LTB4-induced up-regulation of CD11b/CD18 in human neutrophils | Homo sapiens | 8 | ALA1159191 | assay format | Scientific Literature | |
10. | ALA700004 | Functional | Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole blood | 12 | ALA1130879 | tissue-based format | Scientific Literature | ||
11. | ALA702582 | Functional | Inhibition of LTB4-induced CD11b/CD18 integrin up-regulation in human neutrophils | Homo sapiens | 2 | ALA1126386 | assay format | Scientific Literature | |
12. | ALA702583 | Functional | Inhibition of LTB4-induced CD11b/CD18 integrin up-regulation in human neutrophils; not tested | Homo sapiens | 2 | ALA1126386 | assay format | Scientific Literature | |
13. | ALA701232 | Functional | Inhibition of Leukotriene B4 (LTB4) induced chemotaxis. | Homo sapiens | 16 | ALA1128264 | assay format | Scientific Literature | |
14. | ALA699620 | Functional | Inhibition of LTB4 induced expression of human neutrophil integrin CD11b/CD18. | 35 | ALA1128176 | assay format | Scientific Literature | ||
15. | ALA706966 | Binding | Binding affinity for Leukotriene B4 receptor of guinea pig spleen membranes | Cavia porcellus | 13 | ALA1129645 | tissue-based format | Scientific Literature | |
16. | ALA709165 | Binding | Compound was evaluated for its ability to inhibit [3H]LTB4 binding to LTB4 receptors on guinea pig spleen membranes | Cavia porcellus | 6 | ALA1130879 | tissue-based format | Scientific Literature | |
17. | ALA709169 | Binding | Inhibition of specific binding of [3H]-LTB4 to LTB4 receptor in guinea pig lung membranes | Cavia porcellus | 11 | ALA1127113 | cell membrane format | Scientific Literature | |
18. | ALA709172 | Binding | Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. | 23 | ALA1130879 | protein format | Scientific Literature | ||
19. | ALA873016 | Binding | Inhibition of specific binding of [3H]LTB4 to LTB4 receptor in human neutrophils | Homo sapiens | 11 | ALA1127113 | protein format | Scientific Literature | |
20. | ALA711829 | Binding | Inhibition of leukotriene B4 (LTB4) binding to its receptor on intact human neutrophils | 26 | ALA1151094 | protein format | Scientific Literature |