# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3820698 | Binding | Activity at recombinant GGTase1 (unknown origin) using dansyl-GCVLL as co-substrate assessed as protein prenylation at 5 uM incubated for 1.5 hrs by spectrofluorometric method | Homo sapiens | 11 | ALA3817763 | assay format | Scientific Literature | |
2. | ALA3820700 | Binding | Ratio of Kcat to Km for recombinant GGTase1 (unknown origin) using dansyl-GCVLL as co-substrate assessed as protein prenylation by spectrofluorometric method | Homo sapiens | 12 | ALA3817763 | assay format | Scientific Literature | |
3. | ALA3820702 | Binding | Ratio of Kcat to Km for recombinant GGTase1 (unknown origin) using dansyl-GCVLL as co-substrate assessed as protein prenylation by spectrofluorometric method relative to GGPP | Homo sapiens | 11 | ALA3817763 | assay format | Scientific Literature | |
4. | ALA684260 | Binding | Inhibition of human geranylgeranyltransferase-1 | Homo sapiens | 2 | ALA1134196 | protein complex format | Scientific Literature | |
5. | ALA684261 | Binding | Inhibition of geranylgeranyl transferase I (GGTase-I) | 2 | ALA1132268 | protein complex format | Scientific Literature | ||
6. | ALA687553 | Binding | Inhibition of Candida geranylgeranyl transferase I | Candida albicans | 1 | ALA1136060 | protein complex format | Scientific Literature | |
7. | ALA871940 | Binding | Tested for the inhibition of Candida GGTase I in Candida albicans | Candida albicans | 5 | ALA1136060 | protein complex format | Scientific Literature | |
8. | ALA687554 | Binding | Inhibition of Candida geranylgeranyl transferase I at 3 uM | Candida albicans | 3 | ALA1136060 | protein complex format | Scientific Literature | |
9. | ALA687555 | Binding | Tested for the inhibition of Candida GGTase I in Candida albicans at concentration of 3 uM | Candida albicans | 19 | ALA1136060 | protein complex format | Scientific Literature | |
10. | ALA687556 | Binding | Inhibition of human geranylgeranyl transferase I | Homo sapiens | 1 | ALA1136060 | protein complex format | Scientific Literature | |
11. | ALA687557 | Binding | Tested for the selectivity against human geranylgeranyl transferase I | Homo sapiens | 1 | ALA1136060 | protein complex format | Scientific Literature | |
12. | ALA687558 | Functional | Inhibition of geranylgeranylation of the C-terminal CAAX sequence of Rap 1a in PSN-1 cells | Homo sapiens | 3 | ALA1135197 | cell-based format | Scientific Literature | |
13. | ALA687559 | Functional | Tested for GGPTase inhibitory activity measured by the inhibition of geranylgeranylation of the C-terminal CAAX sequence of Rap 1a in PSN-1 cells; ND denotes not determined | Homo sapiens | 14 | ALA1135197 | cell-based format | Scientific Literature | |
14. | ALA681665 | Functional | Inhibition of geranylgeranylation of C-terminal CAAX sequence of Rap 1a in PSN-1 cells | Homo sapiens | 1 | ALA1135197 | cell-based format | Scientific Literature | |
15. | ALA681666 | Functional | Inhibition of geranylgeranylation of C-terminal CAAX sequence of Rap 1a in PSN-1 cells | Homo sapiens | 1 | ALA1135197 | cell-based format | Scientific Literature | |
16. | ALA681667 | Binding | Inhibition of [1-3H]-GGPP incorporation into biotinylated K4B-Ras peptide by geranylgeranyl transferase in the presence of 5 mM ATP | 3 | ALA1135197 | protein complex format | Scientific Literature | ||
17. | ALA681668 | Binding | Inhibition of [1-3H]-GGPP incorporation into biotinylated K4B-Ras peptide by geranylgeranyl transferase in the presence of 5 mM ATP | 15 | ALA1135197 | protein complex format | Scientific Literature | ||
18. | ALA681669 | Binding | Inhibition of [1-3H]-GGPP incorporation into biotinylated K4B-Ras peptide by geranylgeranyl transferase in the presence of 5 mM ATP | 1 | ALA1135197 | protein complex format | Scientific Literature | ||
19. | ALA681670 | Binding | Inhibition of [1-3H]-GGPP incorporation into biotinylated K4B-Ras peptide by geranylgeranyl transferase in the presence of 5 mM ATP | 2 | ALA1135197 | protein complex format | Scientific Literature | ||
20. | ALA686002 | Binding | In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]GGPP into biotinylated peptide corresponding to the C-terminal of human K-Ras. | Homo sapiens | 18 | ALA1136334 | protein complex format | Scientific Literature |