# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3579110 | Binding | Binding affinity to human NPY1 receptor at 1 uM | Homo sapiens | 4 | ALA3576859 | single protein format | Scientific Literature | |
2. | ALA3579807 | Functional | Agonist activity at human neuropeptide Y Y1 receptor expressed in COS-7 cells cotransfected with chimeric Gi/q protein assessed as inositol phosphate accumulation at 1 uM after 2 hrs by anion exchange chromatography | Homo sapiens | 4 | ALA3576822 | cell-based format | Scientific Literature | |
3. | ALA3587177 | Binding | Inhibition of radioligand binding at human neuropeptide Y1 receptor at 10 uM | Homo sapiens | 1 | ALA3585260 | single protein format | Scientific Literature | |
4. | ALA3616218 | Binding | Binding affinity to human Y1 receptor assessed as inhibition of control specific binding at 10 uM | Homo sapiens | 1 | ALA3612012 | single protein format | Scientific Literature | |
5. | ALA3624144 | Binding | Inhibition of human NPY1-R at 10 uM relative to control | Homo sapiens | 1 | ALA3621160 | single protein format | Scientific Literature | |
6. | ALA3743380 | Binding | Inhibition of human neuropeptide Y1 receptor at 10 uM by radioligand binding assay | Homo sapiens | 1 | ALA3739255 | single protein format | Scientific Literature | |
7. | ALA3750344 | Binding | Binding affinity to NPY1R in human SK-N-MC cells after 2 hrs by liquid scintillation counting assay | Homo sapiens | 1 | ALA3745603 | cell-based format | Scientific Literature | |
8. | ALA3750345 | Binding | Binding affinity to NPY1R in human SK-N-MC cells by liquid scintillation counting assay | Homo sapiens | 1 | ALA3745603 | cell-based format | Scientific Literature | |
9. | ALA3750346 | Binding | Displacement of [3H]propionyl-pNPY from NPY1R in HEL cells after 60 to 90 mins by flow cytometric analysis | Homo sapiens | 4 | ALA3745603 | cell-based format | Scientific Literature | |
10. | ALA3750347 | Binding | Displacement of [3H]propionyl-pNPY from NPY1R (unknown origin) | Homo sapiens | 2 | ALA3745603 | single protein format | Scientific Literature | |
11. | ALA3750348 | Binding | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 6 | ALA3745603 | cell-based format | Scientific Literature | |
12. | ALA3750349 | Binding | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 secs by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 6 | ALA3745603 | cell-based format | Scientific Literature | |
13. | ALA3750350 | Binding | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 1 min by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 5 | ALA3745603 | cell-based format | Scientific Literature | |
14. | ALA3750351 | Binding | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 2 mins by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 5 | ALA3745603 | cell-based format | Scientific Literature | |
15. | ALA3750352 | Binding | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 6 | ALA3745603 | cell-based format | Scientific Literature | |
16. | ALA3750353 | Binding | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 mins by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 6 | ALA3745603 | cell-based format | Scientific Literature | |
17. | ALA3750354 | Binding | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 15 mins by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 3 | ALA3745603 | cell-based format | Scientific Literature | |
18. | ALA3750355 | Binding | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 20 mins by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 3 | ALA3745603 | cell-based format | Scientific Literature | |
19. | ALA3750356 | Binding | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 30 mins by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 2 | ALA3745603 | cell-based format | Scientific Literature | |
20. | ALA3750359 | Binding | Displacement of [3H]UR-MK114 from NPY1R in human SK-N-MC cells by radioligand binding assay | Homo sapiens | 8 | ALA3745603 | cell-based format | Scientific Literature |