# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA641402 | F | In vitro efficacy calculated by chlorine current assay on alpha-1-beta-2-gamma-2 (GABA-A) receptor subtype | 52 | assay format | Scientific Literature | |||
2. | ALA643872 | F | Percent stimulation of Cl- current in Xenopus laevis oocytes expressing rat GABA-A alpha-1-beta-2-gamma-2 subunits at 100 uM | Rattus norvegicus | 9 | cell-based format | Scientific Literature | ||
3. | ALA643873 | F | Percent stimulation of 5-alpha-pregnan-3-alpha-ol-20-one elicited Cl- current in Xenopus laevis oocytes expressing rat GABA-A alpha-1-beta-2-gamma-2 subunits at 30 uM | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
4. | ALA643943 | F | Percent stimulation of pentobarbital elicited Cl- current in Xenopus laevis oocytes expressing rat GABA-A alpha-1-beta-2-gamma-2 subunits at 30 uM | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
5. | ALA680662 | B | In vitro current effect against rat GABA receptor alpha-1-beta-2-gamma-2 subunits expressed in Xenopus laevis oocytes at 0.1 uM (ratio +/- compound) | Rattus norvegicus | 18 | cell-based format | Scientific Literature | ||
6. | ALA680810 | B | In vitro current effect against rat GABA receptor alpha-1-beta-2-gamma-2 subunits expressed in Xenopus laevis oocytes at 10 uM (ratio +/- compound) | Rattus norvegicus | 18 | cell-based format | Scientific Literature | ||
7. | ALA680811 | B | In vitro direct current effect against rat GABA receptor alpha-1-beta-2-gamma-2 subunits expressed in Xenopus laevis oocytes at 10 uM (ratio +/- compound, without GABA) | Rattus norvegicus | 18 | cell-based format | Scientific Literature | ||
8. | ALA681939 | B | In vitro current effect against rat GABA receptor alpha-1-beta-2-gamma-2 subunits expressed in Xenopus laevis oocytes at 1 uM (ratio +/- compound) | Rattus norvegicus | 18 | cell-based format | Scientific Literature | ||
9. | ALA682784 | B | Inhibition of [3H]flumazenil specific binding at rat GABA-A alpha-1-beta-2-gamma-2 receptor subunits expressed in HEK293 cells | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
10. | ALA681621 | F | Percent GABA current elicited in Xenopus laevis oocytes expressing rat GABA-A alpha-1-beta-2-gamma-2 subunits at 1 uM [(-)inhibition, (+)stimulation] | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
11. | ALA681622 | F | Percent GABA current elicited in Xenopus laevis oocytes expressing rat GABA-A alpha-1-beta-2-gamma-2 subunits at 10 uM [(-)inhibition, (+)stimulation] | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
12. | ALA681623 | F | Percent GABA current elicited in Xenopus laevis oocytes expressing rat GABA-A alpha-1-beta-2-gamma-2 subunits at 100 uM [(-)inhibition, (+)stimulation] | Rattus norvegicus | 12 | cell-based format | Scientific Literature | ||
13. | ALA681624 | F | Percent GABA current elicited in Xenopus laevis oocytes expressing rat GABA-A alpha-1-beta-2-gamma-2 subunits at 50 uM [(-)inhibition, (+)stimulation] | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
14. | ALA681625 | F | Percent GABA current elicited in Xenopus laevis oocytes expressing rat GABA-A alpha-1-beta-2-gamma-2 subunits at 100 uM [(-)inhibition, (+)stimulation] | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
15. | ALA679466 | B | Displacement of [3H]Ro-151788 from rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cells | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
16. | ALA679467 | B | Displacement of [3H]Ro-151788 from rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cells | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
17. | ALA679468 | B | Binding affinity for recombinant rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cells | Rattus norvegicus | 9 | cell-based format | Scientific Literature | ||
18. | ALA679469 | F | Percent stimulation of GABA-induced currents in Xenopus Oocytes expressing rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits at 200 uM | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
19. | ALA679470 | F | Percent stimulation of GABA-induced currents in Xenopus Oocytes expressing rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits at 100 uM | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
20. | ALA677139 | F | Percent stimulation of GABA-induced currents in Xenopus Oocytes expressing rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits at 100 uM | Rattus norvegicus | 2 | cell-based format | Scientific Literature |