| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA839893 | F | In vitro GABA-mediated chloride current in A293 cells expressing GABA-A benzodiazepine receptor alpha-1-beta-2-gamma-2 subunits at 5 uM | 41 | ALA1132620 | cell-based format | Scientific Literature | ||
| 2. | ALA656593 | F | In vitro GABA-mediated chloride current in A293 cells expressing GABA-A benzodiazepine receptor alpha-1-beta-2-gamma-2 subunits at 5 uM | 63 | ALA1132620 | cell-based format | Scientific Literature | ||
| 3. | ALA685375 | F | Direct activation of Gamma-aminobutyric acid A receptor in the absence of GABA | 1 | ALA1136745 | assay format | Scientific Literature | ||
| 4. | ALA685376 | F | Direct activation of Gamma-aminobutyric acid A receptor in the absence of GABA | 2 | ALA1136745 | assay format | Scientific Literature | ||
| 5. | ALA685377 | F | Maximum activation of Gamma-aminobutyric acid A receptor compared to maximal control GABA current at >320 uM | 1 | ALA1136745 | assay format | Scientific Literature | ||
| 6. | ALA685378 | F | Maximum activation of Gamma-aminobutyric acid A receptor in the absence of GABA compared to 1 mM GABA | 1 | ALA1136745 | assay format | Scientific Literature | ||
| 7. | ALA685379 | F | Maximum activation of Gamma-aminobutyric acid A receptor in the absence of GABA compared to GABA response | 2 | ALA1136745 | assay format | Scientific Literature | ||
| 8. | ALA679559 | F | Ability to affect GABA-induced chloride current in Xenopus oocytes transiently expressing human GABA-A alpha-1-beta-2-gamma-2 receptors using two-electrode voltage-clamp electrophysiology at test concentration of 1 uM | Homo sapiens | 4 | ALA1133060 | cell-based format | Scientific Literature | |
| 9. | ALA676825 | B | Binding affinity for human GABA-A receptor alpha-1-beta-2-gamma-2 expressed in L(tk-) cell membranes | Homo sapiens | 11 | ALA1129572 | cell-based format | Scientific Literature | |
| 10. | ALA682248 | F | Ability to affect GABA-induced chloride current in Xenopus oocytes transiently expressing human GABA-A alpha-1-beta-2-gamma-2 receptors using two-electrode voltage-clamp electrophysiology at test concentration of 3 uM | Homo sapiens | 1 | ALA1133060 | cell-based format | Scientific Literature | |
| 11. | ALA677933 | F | Ability to affect GABA-induced chloride current in Xenopus oocytes transiently expressing human GABA-A alpha-1-beta-2-gamma-2 receptors using two-electrode voltage-clamp electrophysiology at test concentration of 30 uM | Homo sapiens | 1 | ALA1133060 | cell-based format | Scientific Literature | |
| 12. | ALA677847 | B | Binding affinity evaluated by ability to displace [3H]Ro-151788 from recombinant human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2 expressed in L(tk-)cells | 16 | ALA1133060 | cell-based format | Scientific Literature | ||
| 13. | ALA678910 | B | Direct activation of human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2 | 27 | ALA1135513 | protein complex format | Scientific Literature | ||
| 14. | ALA678911 | B | Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2 | 27 | ALA1135513 | protein complex format | Scientific Literature | ||
| 15. | ALA681630 | F | In vitro GABA-mediated chloride current in A293 cells expressing GABA-A benzodiazepine receptor alpha-1-beta-2-gamma-2 subunits at 5 uM | 1 | ALA1132620 | cell-based format | Scientific Literature | ||
| 16. | ALA678810 | B | Modulatory activity against human GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Xenopus laevis Oocytes at 10 uM | Homo sapiens | 5 | ALA1132659 | cell-based format | Scientific Literature | |
| 17. | ALA678811 | B | Modulatory activity against human GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Xenopus laevis Oocytes at 100 uM | Homo sapiens | 6 | ALA1132659 | cell-based format | Scientific Literature | |
| 18. | ALA678812 | B | Modulatory activity against human GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Xenopus laevis Oocytes at 50 uM | Homo sapiens | 6 | ALA1132659 | cell-based format | Scientific Literature | |
| 19. | ALA678813 | B | Effective concentration against human recombinant GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Xenopus oocytes | Homo sapiens | 1 | ALA1136098 | cell-based format | Scientific Literature | |
| 20. | ALA678814 | B | logIC50 (30 uM) GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Xenopus oocytes | Homo sapiens | 1 | ALA1136098 | cell-based format | Scientific Literature |
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