| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA646568 | B | Inhibition of [125I]MAdCAM-Ig binding to human integrin alpha4-beta7 of RPMI-8866 cells | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 2. | ALA640628 | B | Ability to inhibit adhesion of alpha4-beta7 integrin expressing 38-beta7 lymphoma cells to chinese hamster ovary (CHO) cells stably transfected with MAdCAM-1 | 44 | cell-based format | Scientific Literature | |||
| 3. | ALA640629 | B | Inhibition of alpha4-beta7 lymphoma cell binding to CHO-VCAM-1 cells. | 6 | cell-based format | Scientific Literature | |||
| 4. | ALA640630 | B | Inhibition of alpha-4-beta-7/MAdCAM interactions | 6 | protein complex format | Scientific Literature | |||
| 5. | ALA642137 | B | Inhibition of alpha4-beta7 integrin expressing 38-beta7 lymphoma cell adhesion to chinese hamster ovary (CHO) cells expressing MAdCAM-1 (Not tested) | 1 | cell-based format | Scientific Literature | |||
| 6. | ALA643891 | F | Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cells | 16 | cell-based format | Scientific Literature | |||
| 7. | ALA883237 | F | Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cells; In active | 2 | cell-based format | Scientific Literature | |||
| 8. | ALA817231 | B | Inhibition of [125I]-VCAM-Ig binding to human integrin alpha4-beta7 receptor in RPMI-8866 cells | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 9. | ALA817234 | B | Percent inhibition of [125I]MAdCAM-Ig binding to human integrin alpha4-beta7 receptor of RPMI-8866 cells at 100 nM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA817235 | B | Percent inhibition of [125I]VCAM-Ig binding to human integrin alpha4-beta7 receptor of RPMI-8866 cells at 100 nM | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 11. | ALA823097 | B | Binding affinity towards VLA-4 (alpha4 beta7) receptor in human RPMI-8866 B-cell line using [125I]MAdCAM-Ig as radioligand | 41 | assay format | Scientific Literature | |||
| 12. | ALA823098 | B | Binding affinity towards VLA-4 (alpha4 beta7) receptor in human RPMI-8866 B-cell line using [125I]MAdCAM-Ig as radioligand | 1 | assay format | Scientific Literature | |||
| 13. | ALA815330 | B | Inhibition of MadCAM-Ig binding to alpha-4 beta-7 integrin | 5 | protein complex format | Scientific Literature | |||
| 14. | ALA815331 | B | Inhibition of MadCAM-Ig binding to alpha-4 beta-7 integrin; ND=Not determined | 1 | protein complex format | Scientific Literature | |||
| 15. | ALA815332 | B | Inhibition of MadCAM-Ig binding to alpha-4 beta-7 integrin at 0.1 uM | 11 | protein complex format | Scientific Literature | |||
| 16. | ALA815333 | B | Inhibition of MadCAM-Ig binding to alpha-4 beta-7 integrin at 20 uM | 3 | protein complex format | Scientific Literature | |||
| 17. | ALA819917 | B | Ability to block the alpha4-beta7 integrin-MAdCAM-1 binding interaction using a protein ELISA format | 37 | protein complex format | Scientific Literature | |||
| 18. | ALA823551 | B | Alpha4-beta7 integrin binding affinity was determined in duplicate by a radioligand binding assay using [125I]-VCAM-Ig and a suspension of RPMI-8866 cells (a human B cell line alpha-4-beta-1-beta-7+) | 17 | cell-based format | Scientific Literature | |||
| 19. | ALA823552 | B | Inhibition of [125I]VCAM-Ig binding to Alpha4-beta7 integrin of RPMI-8866 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA823553 | B | Inhibition of [125I]VCAM-Ig binding to Alpha4-beta7 integrin of RPMI-8866 cells at 100 mM (inactive) | Homo sapiens | 3 | cell-based format | Scientific Literature |
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