# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA683884 | F | In vitro relative potency to morphine (IC50, 4.4E-8M) in mouse vas deferens was determined; inactive (potentiates contraction at >/=1.6E-6M) | 1 | tissue-based format | Scientific Literature | |||
2. | ALA700603 | F | Evaluated in vivo for the antinociceptive and opioid antagonist assays in ICR male mice, Tail-Flick agonist and antagonist tests was performed | 7 | organism-based format | Scientific Literature | |||
3. | ALA700604 | F | Evaluated in vivo for the antinociceptive and opioid antagonist assays in ICR male mice, Tail-Flick agonist and antagonist tests was performed; IA, Inactive less than 70% of mice affected at 30 mg/kg. | 6 | organism-based format | Scientific Literature | |||
4. | ALA731688 | F | Analgesic Potency in mice | Mus musculus | 6 | assay format | Scientific Literature | ||
5. | ALA878521 | F | Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deference | Mus musculus | 4 | assay format | Scientific Literature | ||
6. | ALA739438 | F | Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deference. | Mus musculus | 1 | assay format | Scientific Literature | ||
7. | ALA741430 | F | In vivo antinociceptive activity was determined upon subcutaneous administration by hot plate assay | Mus musculus | 10 | organism-based format | Scientific Literature | ||
8. | ALA741432 | F | In vivo antinociceptive activity was determined upon subcutaneous administration in the mouse paraphenylquinone writhing test; Inconsistent dose response. | Mus musculus | 2 | organism-based format | Scientific Literature | ||
9. | ALA840877 | F | Analgesic Potency was tested against mice | 53 | assay format | Scientific Literature | |||
10. | ALA744347 | B | Concentration required to inhibit the specific binding of tritiated ligand [3H]DADL to opiate receptor by 50% | 3 | protein format | Scientific Literature | |||
11. | ALA744348 | B | Concentration required to inhibit the specific binding of tritiated ligand [3H]naloxone to opiate receptor by 50% | 1 | protein format | Scientific Literature | |||
12. | ALA748048 | B | Tested for displacement of radioligand [3H]-Naloxone from opiate receptor | 18 | protein format | Scientific Literature | |||
13. | ALA748049 | B | Tested for displacement of radioligand [3H]naloxone from opiate receptor; ND, no data | 1 | protein format | Scientific Literature | |||
14. | ALA748050 | B | Tested for displacement of radioligand [3H]-Naloxone from opiate receptor; value ranges from 7-10 uM | 1 | protein format | Scientific Literature | |||
15. | ALA749838 | B | Concentration required to inhibit the specific binding of tritiated ligand [3H]-naloxone to opiate receptor by 50% | Mus musculus | 1 | protein format | Scientific Literature | ||
16. | ALA754081 | B | Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptor | Mus musculus | 2 | cell-based format | Scientific Literature | ||
17. | ALA754082 | B | Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptors | Mus musculus | 5 | cell-based format | Scientific Literature | ||
18. | ALA754083 | B | Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand singly expressed with delta or kappa receptor | Mus musculus | 4 | cell-based format | Scientific Literature | ||
19. | ALA883563 | B | Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand singly expressed with delta or kappa receptors. | Mus musculus | 3 | cell-based format | Scientific Literature | ||
20. | ALA752108 | F | Compound was tested for irreversible antagonist activity against opioid receptor in mouse vas deferens expressed as IC20 of morphine divided by the compound | 2 | tissue-based format | Scientific Literature |