# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA683884 | Functional | In vitro relative potency to morphine (IC50, 4.4E-8M) in mouse vas deferens was determined; inactive (potentiates contraction at >/=1.6E-6M) | 1 | ALA1122074 | tissue-based format | Scientific Literature | ||
2. | ALA700603 | Functional | Evaluated in vivo for the antinociceptive and opioid antagonist assays in ICR male mice, Tail-Flick agonist and antagonist tests was performed | 7 | ALA1133570 | organism-based format | Scientific Literature | ||
3. | ALA700604 | Functional | Evaluated in vivo for the antinociceptive and opioid antagonist assays in ICR male mice, Tail-Flick agonist and antagonist tests was performed; IA, Inactive less than 70% of mice affected at 30 mg/kg. | 6 | ALA1133570 | organism-based format | Scientific Literature | ||
4. | ALA844061 | Functional | Hot plate test was carried out for mouse injected sc and the antinociceptive activity was determined from the response | 7 | ALA1133570 | organism-based format | Scientific Literature | ||
5. | ALA844062 | Functional | Hot plate test was carried out for mouse injected sc and the antinociceptive activity was determined from the response;IA, Inactive less than 70% of mice affected at 30 mg/kg. | 6 | ALA1133570 | organism-based format | Scientific Literature | ||
6. | ALA842106 | Functional | Tail-flick vs. morphine ED80(morphine sulfate substituted completely) was studied to determine selective in vivo agonist and antagonist activity. | 6 | ALA1133570 | organism-based format | Scientific Literature | ||
7. | ALA845235 | Functional | Narcotic antagonist activity in the mouse tail-flick versus morphine assay | Mus musculus | 1 | ALA1133570 | tissue-based format | Scientific Literature | |
8. | ALA845236 | Functional | Using the PPQ (paraphenylquinone) assay selective opioid receptor agonist activity was established in mice | 11 | ALA1133570 | assay format | Scientific Literature | ||
9. | ALA884907 | Functional | Using the PPQ (paraphenylquinone) assay selective opioid receptor agonist activity was established in mice;IA, Inactive less than 70% of mice affected at 30 mg/kg. | Mus musculus | 1 | ALA1133570 | organism-based format | Scientific Literature | |
10. | ALA845238 | Functional | Using the PPQ (paraphenylquinone) assay selective opioid receptor agonist activity was established in mice | Mus musculus | 1 | ALA1133570 | assay format | Scientific Literature | |
11. | ALA744347 | Binding | Concentration required to inhibit the specific binding of tritiated ligand [3H]DADL to opiate receptor by 50% | 3 | ALA1122736 | protein format | Scientific Literature | ||
12. | ALA744348 | Binding | Concentration required to inhibit the specific binding of tritiated ligand [3H]naloxone to opiate receptor by 50% | 1 | ALA1122736 | protein format | Scientific Literature | ||
13. | ALA748048 | Binding | Tested for displacement of radioligand [3H]-Naloxone from opiate receptor | 18 | ALA1126802 | protein format | Scientific Literature | ||
14. | ALA748049 | Binding | Tested for displacement of radioligand [3H]naloxone from opiate receptor; ND, no data | 1 | ALA1126802 | protein format | Scientific Literature | ||
15. | ALA748050 | Binding | Tested for displacement of radioligand [3H]-Naloxone from opiate receptor; value ranges from 7-10 uM | 1 | ALA1126802 | protein format | Scientific Literature | ||
16. | ALA749838 | Binding | Concentration required to inhibit the specific binding of tritiated ligand [3H]-naloxone to opiate receptor by 50% | Mus musculus | 1 | ALA1122736 | protein format | Scientific Literature | |
17. | ALA754081 | Binding | Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptor | Mus musculus | 2 | ALA1138828 | cell-based format | Scientific Literature | |
18. | ALA754082 | Binding | Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptors | Mus musculus | 5 | ALA1138828 | cell-based format | Scientific Literature | |
19. | ALA754083 | Binding | Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand singly expressed with delta or kappa receptor | Mus musculus | 4 | ALA1138828 | cell-based format | Scientific Literature | |
20. | ALA883563 | Binding | Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand singly expressed with delta or kappa receptors. | Mus musculus | 3 | ALA1138828 | cell-based format | Scientific Literature |