# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA660002 | Binding | Binding affinity was determined by displacement of [3H]P1075 from its binding sites in canine cardiac membranes | Canis lupus familiaris | 15 | ALA1131338 | cell membrane format | Scientific Literature | |
2. | ALA859322 | Functional | In vitro ATP-sensitive potassium channel (KATP) activity in cells expressing human KATP channels Kir6.2 and sulfonylurea receptor 2B | Homo sapiens | 22 | ALA1148468 | assay format | Scientific Literature | |
3. | ALA700931 | Functional | In vitro ATP-sensitive potassium channel (KATP) activity in cells expressing human KATP channels Kir6.2 and sulfonylurea receptor 2B | Homo sapiens | 1 | ALA1148468 | assay format | Scientific Literature | |
4. | ALA841447 | Binding | Hill Coefficient calculated by curve fitting of data to a single binding site model | 12 | ALA1131338 | protein complex format | Scientific Literature | ||
5. | ALA801445 | Binding | Inhibition of human SUR2A/Kir6.2 expressed in Xenopus oocytes | Homo sapiens | 1 | ALA1134478 | cell-based format | Scientific Literature | |
6. | ALA805672 | Binding | Inhibition of human SUR2A/Kir6.2 expressed in Xenopus oocytes | Homo sapiens | 1 | ALA1134478 | cell-based format | Scientific Literature | |
7. | ALA805673 | Binding | Inhibition of SUR2B/Kir6.2 | Homo sapiens | 1 | ALA1134478 | protein complex format | Scientific Literature | |
8. | ALA805674 | Binding | Inhibition of SUR2B/Kir6.2 | Rattus norvegicus | 1 | ALA1134478 | protein complex format | Scientific Literature | |
9. | ALA908895 | Functional | Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay | Homo sapiens | 78 | ALA1137338 | cell-based format | Scientific Literature | |
10. | ALA908896 | Functional | Ability to open human urinary bladder Kir6.2 containing SUR2B in Ltk cells by FLIPR assay relative to P1075 | Homo sapiens | 71 | ALA1137338 | cell-based format | Scientific Literature | |
11. | ALA908308 | Functional | Activity against pig bladder KATP channel opening assessed as ability to relax field-stimulated pig detrusor | Sus scrofa | 22 | ALA1137338 | assay format | Scientific Literature | |
12. | ALA908306 | Functional | Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contraction | Sus scrofa | 11 | ALA1137338 | assay format | Scientific Literature | |
13. | ALA907148 | Functional | Activity against pig bladder KATP channel opening assessed as ability to relax field-stimulated pig detrusor relative to P1075 | Sus scrofa | 22 | ALA1137338 | assay format | Scientific Literature | |
14. | ALA907149 | Functional | Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contraction relative to P1075 | Sus scrofa | 11 | ALA1137338 | assay format | Scientific Literature | |
15. | ALA1918789 | Binding | Inhibition of Kir6.2/SUR2A at 10 uM after 5 mins by patch clamp assay | 1 | ALA1914304 | assay format | Scientific Literature | ||
16. | ALA1918928 | Binding | Inhibition of human kir6.2/SUR2A ion channel coexpressed in human HEK293 cells after 5 mins by patch clamp assay | Homo sapiens | 4 | ALA1914304 | cell-based format | Scientific Literature |