# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA767695 | F | In vivo inhibion of pyruvate dehydrogenase kinase, increased oxidation of lactate | Homo sapiens | 8 | organism-based format | Scientific Literature | ||
2. | ALA767696 | B | Inhibitory activity against Pyruvate dehydrogenase kinase | Sus scrofa | 1 | protein format | Scientific Literature | ||
3. | ALA767697 | B | In vitro inhibitory activity against Pyruvate dehydrogenase kinase by primary enzymatic assay | Sus scrofa | 18 | protein format | Scientific Literature | ||
4. | ALA767698 | B | Inhibitory activity against Pyruvate dehydrogenase kinase by primary enzymatic assay; inactive | Sus scrofa | 2 | protein format | Scientific Literature | ||
5. | ALA764813 | B | In vitro inhibitory activity against pyruvate dehydrogenase kinase was determined | 12 | protein format | Scientific Literature | |||
6. | ALA764814 | B | In vitro inhibitory activity against pyruvate dehydrogenase kinase was determined; Inactive at 1 mM concentration | 12 | protein format | Scientific Literature | |||
7. | ALA769458 | B | Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assay | Sus scrofa | 90 | protein format | Scientific Literature | ||
8. | ALA769459 | B | In vitro inhibition of pyruvate dehydrogenase kinase (PDHK) in primary enzymatic assay; Inactive | Sus scrofa | 2 | protein format | Scientific Literature | ||
9. | ALA767850 | B | In vitro inhibition of pyruvate dehydrogenase kinase (PDHK) in primary enzymatic assay; Inactive | Sus scrofa | 9 | protein format | Scientific Literature | ||
10. | ALA3721114 | B | Inhibition of pyruvate dehydrogenase kinase (unknown origin) assessed as reduction in E1 phosphorylation incubated for 1 hr by DELFIA method | Homo sapiens | 19 | protein format | Patent Bioactivity Data | ||
11. | ALA3721115 | B | Binding affinity to pyruvate dehydrogenase kinase (unknown origin) by VER-00160364 probe based fluorescence polarization assay | Homo sapiens | 269 | assay format | Patent Bioactivity Data | ||
12. | ALA3721116 | B | Inhibition of pyruvate dehydrogenase kinase in human PC3 cells incubated for 90 mins by phospho(Ser293)E1alpha MSP ELISA method | Homo sapiens | 30 | cell-based format | Patent Bioactivity Data | ||
13. | ALA3734254 | B | Inhibition of pyruvate dehydrogenase kinase in human PC3 cells incubated for 90 mins by phospho(Ser293)E1alpha MSP ELISA method | Homo sapiens | 30 | cell-based format | Patent Bioactivity Data | ||
14. | ALA4311232 | B | Inhibition of PDK in human NCI-H1975 cells assessed as reduction in phosphorylated S293 PDC E1 level at 10 uM by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
15. | ALA4311233 | B | Inhibition of PDK in human NCI-H1975 cells assessed as reduction in phosphorylated S293 PDC E1 level by ELISA | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA4311234 | B | Inhibition of PDK in human NCI-H1975 cells assessed as reduction in phosphorylated S293 PDC E1 level by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA4311241 | B | Inhibition of PDK in human NCI-H1975 cells assessed as switch of pyruvate metabolism from lactate production to oxidative phosphorylation by measuring increase in ROS production at 1 to 10 uM measured after 4 hrs by DCFH-DA dye based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA4311242 | B | Inhibition of PDK in human NCI-H1975 cells assessed as switch of pyruvate metabolism from lactate production to oxidative phosphorylation by measuring increase in oxygen consumption rate measured after 2 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4311243 | B | Inhibition of PDK in human NCI-H1975 cells assessed as switch of pyruvate metabolism from lactate production to oxidative phosphorylation by measuring decrease in lactate production at 1 to 10 uM measured after 4 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA4369509 | B | Inhibition of PDK in human NCI-H1975 cells assessed as reduction in PDC phosphorylation at 2 uM measured after 12 hrs under hypoxic condition by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature |