# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3429850 | Binding | Inhibition of SAPK/JNK phosphorylation in human MDA-MB-231 cells at 7.5 to 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA3425411 | cell-based format | Scientific Literature | |
2. | ALA3429851 | Binding | Inhibition of SAPK/JNK phosphorylation in human MDA-MB-231 cells at 5 to 7.5 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3425411 | cell-based format | Scientific Literature | |
3. | ALA3578902 | Binding | Competitive binding affinity to JNK in human A375 cells after 15 mins in presence of ATP analogue | Homo sapiens | 1 | ALA3576847 | cell-based format | Scientific Literature | |
4. | ALA3579066 | Binding | Inhibition of JNK in human SH-SY5Y cells assessed as inhibition of 6-OHDA-induced c-Jun phosphorylation preincubated for 1 hr followed by 6-OHDA-induction measured after 4 to 5 hrs by Western blot analysis | Homo sapiens | 6 | ALA3576797 | cell-based format | Scientific Literature | |
5. | ALA3579067 | Binding | Inhibition of JNK in human SH-SY5Y cells assessed as inhibition of 6-OHDA-induced mitochondrial membrane depolarization preincubated for 30 mins followed by 6-OHDA-induction measured after 4 to 5 hrs by mitoTracker orange CMTRos dye-based fluorescence assay | Homo sapiens | 2 | ALA3576797 | cell-based format | Scientific Literature | |
6. | ALA3627285 | Binding | Activation of JNK in human Caki1 cells assessed as increase in JNK phosphorylation at 250 to 1000 pM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3621165 | cell-based format | Scientific Literature | |
7. | ALA3627303 | Binding | Activation of JNK in human Caki1 cells assessed as increase in phosphorylated c-Jun expression at 250 to 1000 pM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3621165 | cell-based format | Scientific Literature | |
8. | ALA3627312 | Binding | Activation of JNK in NNMT siRNA-transfected human Caki1 cells assessed as enzyme phosphorylation at 500 pM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3621165 | cell-based format | Scientific Literature | |
9. | ALA3631026 | Binding | Inhibition of Myc CA-JNK (unknown origin) transfected in HEK293 cells assessed as reduction of phosphorylation of c-Jun at 10 uM incubated for 5 hrs measured by Western blot analysis | Homo sapiens | 1 | ALA3627690 | cell-based format | Scientific Literature | |
10. | ALA3761130 | Binding | Inhibition of PMACI-induced phosphorylation of JNK in HMC1 cells at 12.5 to 50 uM pretreated for 30 mins followed by addition of PMACI incubated for 15 mins by Western blot analysis | Homo sapiens | 1 | ALA3758130 | cell-based format | Scientific Literature | |
11. | ALA3760573 | Binding | Inhibition of JNK phosphorylation in human BV2 cells at 20 to 80 uM pretreated for 30 mins followed by LPS stimulation for 30 mins by Western blot analysis | Homo sapiens | 1 | ALA3758144 | cell-based format | Scientific Literature | |
12. | ALA3773541 | Binding | Induction of JNK phosphorylation in human HCT116 cells at 5 uM after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
13. | ALA3783074 | Binding | Induction of JNK phosphorylation in human SEM cells at 8 uM after 3 to 12 hrs by immunoblot analysis | Homo sapiens | 1 | ALA3779792 | cell-based format | Scientific Literature | |
14. | ALA3783075 | Binding | Induction of JNK phosphorylation in human NALM6 cells at 4.5 uM after 3 to 12 hrs by immunoblot analysis | Homo sapiens | 1 | ALA3779792 | cell-based format | Scientific Literature | |
15. | ALA3807462 | Binding | Inhibition of JNK phosphorylation in human HL60 cells at 0.1 to 1 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA3804789 | cell-based format | Scientific Literature | |
16. | ALA3807463 | Binding | Inhibition of JNK in human HL60 cells assessed as increase in phosphorylated STAT3 expression at 0.1 to 1 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA3804789 | cell-based format | Scientific Literature | |
17. | ALA702352 | Binding | Inhibition of JNK, c-Jun N-terminal kinase | 1 | ALA1136216 | protein format | Scientific Literature | ||
18. | ALA872577 | Binding | Inhibition of c-Jun N-terminal kinase | Aplidium | 1 | ALA1148433 | protein format | Scientific Literature | |
19. | ALA821145 | Binding | Inhibition of c-Jun N-terminal kinase at 10 uM | Homo sapiens | 5 | ALA1134212 | protein format | Scientific Literature | |
20. | ALA818499 | Binding | Inhibition of c-Jun N-terminal kinase | 1 | ALA1145099 | protein format | Scientific Literature |