# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615180 | Functional | Functional antagonism by electrical assays in Xenopus oocytes expressing 1A/2A NMDA receptor subtype | Rattus norvegicus | 13 | ALA1131085 | cell-based format | Scientific Literature | |
2. | ALA1041649 | Functional | Antagonist activity at rat recombinant NR1/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at 3 uM by two electrode voltage clamp method relative to control | Rattus norvegicus | 23 | ALA1152519 | cell-based format | Scientific Literature | |
3. | ALA1040709 | Functional | Antagonist activity at rat recombinant NR1/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA1152519 | cell-based format | Scientific Literature | |
4. | ALA1062125 | Functional | Agonist activity at ConA-treated rat NR1/NR2A expressed in Xenopus laevis oocytes assessed as glycine-induced maximal current by two-electrode voltage clamp method | Rattus norvegicus | 3 | ALA1151943 | cell-based format | Scientific Literature | |
5. | ALA1057732 | Binding | Activity at rat NR1/NR2A receptor expressed in Xenopus oocytes assessed as inhibition of glycine-induced electrophysiological response | Rattus norvegicus | 3 | ALA1151901 | cell-based format | Scientific Literature | |
6. | ALA1036607 | Binding | Inhibition of rat recombinant NR1/NR2A receptor expressed in Xenopus oocytes assessed as inhibition of glutamate and glycine-induced evoked current at 3uM by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA1140127 | cell-based format | Scientific Literature | |
7. | ALA747509 | Functional | Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1/2A. | 35 | ALA1132364 | assay format | Scientific Literature | ||
8. | ALA747510 | Functional | Antagonistic activity against rat N-methyl-D-aspartate glutamate receptor 1/2A, expressed in Xenopus oocytes | 11 | ALA1132273 | cell-based format | Scientific Literature | ||
9. | ALA753011 | Binding | Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype. | 18 | ALA1132970 | cell-based format | Scientific Literature | ||
10. | ALA753016 | Functional | In vitro inhibitory concentration against NMDA responses at cloned NR1A/2A receptors expressed in Xenopus oocytes | Rattus norvegicus | 8 | ALA1132328 | cell-based format | Scientific Literature | |
11. | ALA753017 | Functional | Antagonistic activity against rat NR1A/2A receptor, expressed in Xenopus oocytes | 21 | ALA1132273 | cell-based format | Scientific Literature | ||
12. | ALA1015728 | Binding | Activity at rat recombinant NR1/NR2A receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp electrophysiology | Rattus norvegicus | 6 | ALA1155079 | cell-based format | Scientific Literature | |
13. | ALA1015729 | Binding | Activity at rat recombinant NR1/NR2A receptor expressed in Xenopus oocytes by two voltage clamp electrophysiology relative to glutamate | Rattus norvegicus | 5 | ALA1155079 | cell-based format | Scientific Literature | |
14. | ALA829801 | Binding | Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xenopus oocytes | Rattus norvegicus | 20 | ALA1143579 | cell-based format | Scientific Literature | |
15. | ALA833556 | Binding | Mean inhibitory concentration against rat N-methyl-D-aspartate (NMDA) glutamate receptor 1a/2A expressed in Xenopus oocytes | Rattus norvegicus | 3 | ALA1144373 | cell-based format | Scientific Literature | |
16. | ALA914285 | Functional | Antagonist activity at rat recombinant NR1/NR2A receptor expressed in EcR293 cells assessed as inhibition of NMDA-evoked ion currents at 10 uM by patch clamp technique | Rattus norvegicus | 1 | ALA1142862 | cell-based format | Scientific Literature | |
17. | ALA901120 | Binding | Blockade of L-glutamate/glycine-activated rat NR1/NR2A NMDA receptor expressed in Xenopus oocytes | Rattus norvegicus | 8 | ALA1138312 | cell-based format | Scientific Literature | |
18. | ALA1104016 | Functional | Agonist activity at rat NR1/NR2A receptor expressed in BHK21 cells assessed as change in intracellular calcium levels by FLIPR assay | Rattus norvegicus | 2 | ALA1157748 | cell-based format | Scientific Literature | |
19. | ALA1104017 | Functional | Agonist activity at rat NR1/NR2A receptor expressed in BHK21 cells assessed as change in intracellular calcium levels at 1000 uM by FLIPR assay | Rattus norvegicus | 2 | ALA1157748 | cell-based format | Scientific Literature | |
20. | ALA1120790 | Functional | Agonist activity at rat NR1/NR2A receptor expressed in BHK21 cells assessed as change in intracellular calcium levels by FLIPR assay relative to (S)-Glu | Rattus norvegicus | 1 | ALA1157748 | cell-based format | Scientific Literature |