# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3428224 | Binding | Inhibition of AMPK (unknown origin) assessed as remaining activity at 100 uM by radioactive filter binding assay in presence of [33P]-ATP relative to control | Homo sapiens | 16 | ALA3425453 | protein complex format | Scientific Literature | |
2. | ALA3595426 | Binding | Inhibition of human AMPK A1/B1/G1 at 0.1 uM relative to control | Homo sapiens | 1 | ALA3593229 | protein complex format | Scientific Literature | |
3. | ALA3599527 | Binding | Inhibition of AMPK (unknown origin) at 0.5 uM relative to control | Homo sapiens | 3 | ALA3596148 | protein complex format | Scientific Literature | |
4. | ALA3606889 | Binding | Inhibition of AMPK (unknown origin) at 2 uM by radioactive filter-binding assay | Homo sapiens | 1 | ALA3603808 | protein complex format | Scientific Literature | |
5. | ALA3607373 | Binding | Inhibition of AMPK (unknown origin) at 250 nM by radioactive filter-binding assay | Homo sapiens | 1 | ALA3603808 | protein complex format | Scientific Literature | |
6. | ALA3635460 | Binding | Activation of AMPK in human HepG2 cells assessed as reduction of gluconeogenesis at 50 uM after 24 hrs by enzymatic colorimetric assay relative to control | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
7. | ALA3635461 | Binding | Activation of AMPK in human HepG2 cells assessed as reduction of gluconeogenesis at 100 uM after 24 hrs by enzymatic colorimetric assay relative to control | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
8. | ALA3635462 | Binding | Activation of AMPK in human HepG2 cells assessed as reduction of gluconeogenesis at 1 mM after 24 hrs by enzymatic colorimetric assay | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
9. | ALA3635463 | Binding | Activation of AMPK in human TE671 cells assessed as increase in glucose uptake by measuring intracellular 2-NBDG level at 100 uM after 24 hrs by fluorimetric analysis relative to control | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
10. | ALA3635660 | Binding | Activation of AMPK in human TE671 cells assessed as increase in glucose uptake by measuring intracellular 2-NBDG level at 100 uM after 24 hrs by fluorimetric analysis in presence of insulin relative to control | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
11. | ALA3635661 | Binding | Induction of AMPK phosphorylation at Thr172 in human HepG2 cells at 50 to 100 uM after 4 hrs by immunoblot analysis | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
12. | ALA3635662 | Binding | Induction of AMPK phosphorylation at Thr172 in human TE671 cells at 50 to 100 uM after 4 hrs by immunoblot analysis | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
13. | ALA3635663 | Binding | Activation of AMPK (unknown origin) by luminescence assay | Homo sapiens | 2 | ALA3632550 | protein complex format | Scientific Literature | |
14. | ALA3635666 | Binding | Induction of AMPK phosphorylation at Thr172 in human HepG2 cells at 50 to 100 uM after 4 hrs by immunoblot analysis in presence of CAMMK-beta inhibitor STO-609 | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
15. | ALA3635667 | Binding | Induction of AMPK phosphorylation at Thr172 in human TE671 cells at 50 to 100 uM after 4 hrs by immunoblot analysis in presence of CAMMK-beta inhibitor STO-609 | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
16. | ALA3635668 | Binding | Activation of AMPK in human HepG2 cells assessed as induction of CRTC2 phosphorylation at 100 uM after 4 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
17. | ALA3635992 | Binding | Activation of AMPK in human HepG2 cells assessed as induction of HDAC5 phosphorylation at 100 uM after 4 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
18. | ALA3635993 | Binding | Activation of AMPK in human HepG2 cells assessed as decrease in CRTC2 level in nucleus at 100 uM after 4 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
19. | ALA3635994 | Binding | Activation of AMPK in human HepG2 cells assessed as decrease in HDAC5 level in nucleus at 100 uM after 4 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature | |
20. | ALA3635995 | Binding | Activation of AMPK in human HepG2 cells assessed as reduction of CREB transactivation at 50 to 100 uM after 24 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 1 | ALA3632550 | cell-based format | Scientific Literature |