# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615182 | F | Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2C NMDA receptor | Rattus norvegicus | 13 | ALA1131085 | cell-based format | Scientific Literature | |
2. | ALA747109 | F | Dissociation constant for NMDA receptor glycine sites from inhibition of currents activated by 1 uM glycine and 100 uM glutamate in Xenopus oocytes expressing the cloned rat N-methyl-D-aspartate glutamate receptor subunit combination NR1a/2C | Rattus norvegicus | 1 | ALA1129955 | cell-based format | Scientific Literature | |
3. | ALA749383 | F | Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1/2C. | 34 | ALA1132364 | assay format | Scientific Literature | ||
4. | ALA749384 | F | Antagonistic activity against rat N-methyl-D-aspartate glutamate receptor 1/2C expressed in Xenopus oocytes | 11 | ALA1132273 | cell-based format | Scientific Literature | ||
5. | ALA747991 | F | Dissociation constant for NMDA receptor glycine sites as inhibition of currents activated by 1 uM glycine and 100 uM glutamate in Xenopus oocytes expressing the cloned rat N-methyl-D-aspartate glutamate receptor subunit combination NR1a/2C | Rattus norvegicus | 1 | ALA1129955 | cell-based format | Scientific Literature | |
6. | ALA752245 | B | Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype. | 18 | ALA1132970 | cell-based format | Scientific Literature | ||
7. | ALA752250 | F | In vitro inhibitory concentration against NMDA responses at NR1A/2C receptors expressed in Xenopus oocytes | Rattus norvegicus | 8 | ALA1132328 | cell-based format | Scientific Literature | |
8. | ALA752251 | F | The compound was tested for antagonistic activity against rat NR1A/2C receptor expressed in Xenopus oocytes | 22 | ALA1132273 | cell-based format | Scientific Literature | ||
9. | ALA828983 | B | Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xenopus oocytes | Rattus norvegicus | 21 | ALA1143579 | cell-based format | Scientific Literature | |
10. | ALA833558 | B | Mean inhibitory concentration against rat N-methyl-D-aspartate (NMDA) glutamate receptor 1a/2C expressed in Xenopus oocytes | Rattus norvegicus | 3 | ALA1144373 | cell-based format | Scientific Literature | |
11. | ALA1015733 | B | Activity at rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp electrophysiology | Rattus norvegicus | 6 | ALA1155079 | cell-based format | Scientific Literature | |
12. | ALA1015734 | B | Activity at rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes by two voltage clamp electrophysiology relative to glutamate | Rattus norvegicus | 5 | ALA1155079 | cell-based format | Scientific Literature | |
13. | ALA1036608 | B | Inhibition of rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes assessed as inhibition of glutamate and glycine-induced evoked current at 3uM by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA1140127 | cell-based format | Scientific Literature | |
14. | ALA1041651 | F | Antagonist activity at rat recombinant NR1/NR2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at 3 uM by two electrode voltage clamp method relative to control | Rattus norvegicus | 23 | ALA1152519 | cell-based format | Scientific Literature | |
15. | ALA1040710 | F | Antagonist activity at rat recombinant NR1/NR2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA1152519 | cell-based format | Scientific Literature | |
16. | ALA1219912 | F | Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp electrophysiology | Rattus norvegicus | 94 | ALA1212913 | cell-based format | Scientific Literature | |
17. | ALA1954479 | F | Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by two-electrode voltage-clamp electrophysiology assay | Rattus norvegicus | 25 | ALA1949555 | cell-based format | Scientific Literature | |
18. | ALA1954484 | F | Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response at 100 uM by two-electrode voltage-clamp electrophysiology assay | Rattus norvegicus | 3 | ALA1949555 | cell-based format | Scientific Literature | |
19. | ALA2351864 | B | Ratio of compound Imax to glutamate Imax for rat recombinant wild type GluN1/GluN2C receptor | Rattus norvegicus | 7 | ALA2346561 | protein complex format | Scientific Literature | |
20. | ALA2351868 | B | Agonist activity at rat recombinant wild type GluN1/GluN2C receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp technique | Rattus norvegicus | 7 | ALA2346561 | cell-based format | Scientific Literature |