# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA653239 | F | Inhibition of Beta-cell KATP channel | 7 | ALA1134916 | assay format | Scientific Literature | ||
2. | ALA653240 | F | Percentage of maximal agonistic response of Beta-cell KATP channel as compared to diazoxide (50 uM) | 7 | ALA1134916 | assay format | Scientific Literature | ||
3. | ALA858103 | F | Negative log EC50 for Beta-cell KATP channel | 5 | ALA1134916 | assay format | Scientific Literature | ||
4. | ALA700928 | F | Maximum activation of human KATP (SUR1/Kir6.2) channel expressed in Xenopus oocytes | Homo sapiens | 8 | ALA1149217 | cell-based format | Scientific Literature | |
5. | ALA700929 | F | Percent maximal agonist response of human KATP (SUR1/Kir6.2) channel expressed in Xenopus oocytes | Homo sapiens | 5 | ALA1149217 | cell-based format | Scientific Literature | |
6. | ALA700930 | F | Percent maximal agonist response of human KATP (SUR1/Kir6.2) channel expressed in Xenopus oocytes at 30 uM | Homo sapiens | 2 | ALA1149217 | cell-based format | Scientific Literature | |
7. | ALA801444 | B | Inhibition of human SUR1/Kir6.2 expressed in CHO cells | Homo sapiens | 2 | ALA1134478 | cell-based format | Scientific Literature | |
8. | ALA810540 | B | Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without ATP | Homo sapiens | 2 | ALA1135780 | cell-based format | Scientific Literature | |
9. | ALA810541 | B | Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high affinity state with 2 mM MgATP | Homo sapiens | 9 | ALA1135780 | cell-based format | Scientific Literature | |
10. | ALA810542 | B | Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low affinity state with 2 mM MgATP | Homo sapiens | 9 | ALA1135780 | cell-based format | Scientific Literature | |
11. | ALA810543 | B | Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without ATP | Homo sapiens | 8 | ALA1135780 | cell-based format | Scientific Literature | |
12. | ALA810544 | B | Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low affinity state with 2 mM MgATP | Homo sapiens | 1 | ALA1135780 | cell-based format | Scientific Literature | |
13. | ALA810545 | B | Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high affinity state with 2 mM MgATP; NT is Not tested | Homo sapiens | 1 | ALA1135780 | cell-based format | Scientific Literature | |
14. | ALA810546 | B | Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low affinity state with 2 mM MgATP; NT is Not tested | Homo sapiens | 1 | ALA1135780 | cell-based format | Scientific Literature | |
15. | ALA810547 | B | Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without ATP; NT is Not tested | Homo sapiens | 1 | ALA1135780 | cell-based format | Scientific Literature | |
16. | ALA824661 | F | Antiarrhythmic effect in hSUR1/hKir6.2 (pancreatic KATP channel) transfected in CHO cells at a dose of 0.1 uM | Homo sapiens | 39 | ALA1134386 | cell-based format | Scientific Literature | |
17. | ALA843352 | F | Antiarrhythmic effect in hSUR1/hKir6.2 (pancreatic KATP channel) transfected in CHO cells at a dose of 1 uM | Homo sapiens | 39 | ALA1134386 | cell-based format | Scientific Literature | |
18. | ALA843353 | F | Antiarrhythmic effect in hSUR1/hKir6.2 (pancreatic KATP channel) transfected in CHO cells at a dose of 10 uM | Homo sapiens | 39 | ALA1134386 | cell-based format | Scientific Literature | |
19. | ALA843354 | F | Antiarrhythmic effect in hSUR1/hKir6.2 (pancreatic KATP channel) transfected in CHO cells at 10 nM | Homo sapiens | 1 | ALA1134386 | cell-based format | Scientific Literature | |
20. | ALA843355 | F | Antiarrhythmic effect in hSUR1/hKir6.2 (pancreatic KATP channel) transfected in CHO cells at 1 nM | Homo sapiens | 1 | ALA1134386 | cell-based format | Scientific Literature |