# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA754355 | B | Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 2 | 21 | ALA1145090 | single protein format | Scientific Literature | ||
2. | ALA935419 | B | Binding affinity at human NTS2 receptor | Homo sapiens | 1 | ALA1144667 | single protein format | Scientific Literature | |
3. | ALA935421 | B | Displacement of [125I]Tyr3NT from human NTS2 receptor expressed in COS7 cells | Homo sapiens | 2 | ALA1144667 | cell-based format | Scientific Literature | |
4. | ALA1176542 | B | Binding affinity to human NTR2 by gamma counting | Homo sapiens | 1 | ALA1177699 | single protein format | Scientific Literature | |
5. | ALA1768190 | B | Displacement of [3H]NT from human NTS2 receptor expressed in HEK293 cells | Homo sapiens | 35 | ALA1765055 | cell-based format | Scientific Literature | |
6. | ALA1768194 | F | Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activity | Homo sapiens | 5 | ALA1765055 | cell-based format | Scientific Literature | |
7. | ALA1768195 | B | Ratio of compound EC50 to neurotensin EC50 for human NTS2 receptor | Homo sapiens | 4 | ALA1765055 | single protein format | Scientific Literature | |
8. | ALA1768196 | F | Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activity at 3 uM in presence of SR142948A | Homo sapiens | 1 | ALA1765055 | cell-based format | Scientific Literature | |
9. | ALA2405881 | B | Binding affinity to NTR2 (unknown origin) | Homo sapiens | 1 | ALA2401662 | single protein format | Scientific Literature | |
10. | ALA2433843 | B | Agonist activity at NTR2 (unknown origin) expressed in human U2OS cells coexpressing beta-arrestin by GFP reporter gene assay | Homo sapiens | 45 | ALA2429761 | cell-based format | Scientific Literature | |
11. | ALA3089086 | B | Displacement of [3H]NT(8 to 13) from human NTS2 receptor expressed in HEK293 cells | Homo sapiens | 4 | ALA3085769 | cell-based format | Scientific Literature | |
12. | ALA3101953 | B | Agonist activity at NTR2 in human U2OS cells after 1 hr by beta-arrestin GFP reporter gene assay | Homo sapiens | 2 | ALA3098058 | cell-based format | Scientific Literature | |
13. | ALA3588723 | B | Inverse agonist activity at NTSR2 (unknown origin) expressed in HEK293 cells assessed as suppression of constitutive receptor activity by NFAT-RE-luciferase reporter gene assay | Homo sapiens | 14 | ALA3585260 | cell-based format | Scientific Literature | |
14. | ALA3625239 | B | Displacement of [125I]-Tyr3-NT from human NTS2 receptor expressed in 1321N1 cell membranes incubated for 30 mins by gamma-counting based competitive radioligand binding assay | Homo sapiens | 7 | ALA3621076 | cell-based format | Scientific Literature | |
15. | ALA3791112 | B | Displacement of [3H]NT(8 to 13 residues) from human NTSR2 expressed in HEK293 cell membranes | Homo sapiens | 9 | ALA3784921 | cell-based format | Scientific Literature | |
16. | ALA3871847 | B | Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting | Homo sapiens | 16 | ALA3871285 | cell-based format | Scientific Literature | |
17. | ALA4051202 | B | Displacement of 125I-[Tyr3]-NT from human NTS2 receptor expressed in human 1321N1 cell membranes after 30 mins by gamma counting analysis | Homo sapiens | 7 | ALA4049427 | cell-based format | Scientific Literature | |
18. | ALA4051209 | B | Displacement of 125I-[Tyr3]-NT from human NTS2 receptor | Homo sapiens | 1 | ALA4049427 | single protein format | Scientific Literature | |
19. | ALA4338741 | B | Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation counter analysis | Homo sapiens | 9 | ALA4334537 | cell-based format | Scientific Literature | |
20. | ALA4375459 | B | Allosteric modulation of NTR2 (unknown origin) assessed as induction of NT (8 to 13) peptide-mediated beta-arrestin recruitment at >80 uM by pathhunter assay | Homo sapiens | 42 | ALA4373709 | single protein format | Scientific Literature |