# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA656307 | F | Compound was evaluated for accumulation of [3H]- IP in CHO (CaSR) cells expressing rat cloned calcium sensing receptor | 19 | cell-based format | Scientific Literature | |||
2. | ALA656308 | F | Maximal stimulation of [3H]-inositol phosphates production in CHO cells expressing rat Calcium sensing receptor (CaSR) at 10 mM [Ca2+] | 17 | cell-based format | Scientific Literature | |||
3. | ALA656309 | F | Ability to stimulate [3H]inositol phosphates accumulation in CHO cells expressing rat Calcium sensing receptor (CaSR) at 2 mM [Ca2+] | 2 | cell-based format | Scientific Literature | |||
4. | ALA870549 | F | Inhibition of extracellular calcium-induced inositol triphosphate generation in rat MTC cells expressing calcium-sensing receptor | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
5. | ALA870363 | F | Activity at rat CaSR in CHO cells assessed as inhibition of calcium ion-induced [3H]inositol phosphate accumulation at 10 uM | Rattus norvegicus | 31 | cell-based format | Scientific Literature | ||
6. | ALA870365 | F | Activity at rat CaSR in CHO cells assessed as inhibition of calcium ion-induced [3H]inositol phosphate accumulation at 1 uM | Rattus norvegicus | 23 | cell-based format | Scientific Literature | ||
7. | ALA866784 | F | Activity at rat CaSR in CHO cells assessed as inhibition of calcium ion-induced [3H]inositol phosphate accumulation | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
8. | ALA1785978 | F | Negative allosteric modulator activity at rat calcium sensing receptor expressed in HEK cells | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
9. | ALA1804306 | F | Agonist activity at rat CaSR expressed in CHO cells assessed as increase of calcium-induced inositol phosphate accumulation at 10 uM after 24 hrs by HTRF assay relative to calcium | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
10. | ALA3637423 | F | Antagonist activity at rat CaSR expressed in HEK293 cells assessed as inhibition of Ca2+-induced inositol monophosphate accumulation after 1 hr by FRET assay | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
11. | ALA3755700 | F | Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 10 uM in presence of 3 mM extracellular Ca2+ by IP-one assay | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
12. | ALA3755701 | F | Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 3 uM in presence of 3 mM extracellular Ca2+ by IP-one assay | Rattus norvegicus | 18 | cell-based format | Scientific Literature | ||
13. | ALA3755702 | F | Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 10 uM in presence of 2 mM extracellular Ca2+ by IP-one assay | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
14. | ALA3755703 | F | Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 3 uM in presence of 2 mM extracellular Ca2+ by IP-one assay | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
15. | ALA3755704 | F | Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 0.1 uM in presence of 3 mM extracellular Ca2+ by IP-one assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
16. | ALA3755705 | F | Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one assay | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
17. | ALA4047176 | F | Agonist activity at rat CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
18. | ALA4122630 | F | Agonist activity at CaSR in rat parathyroid cells assessed as inhibition of PTH (1 to 84 residues) production in presence of Cacl2 by ELISA | Rattus norvegicus | 15 | cell-based format | Scientific Literature |