# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA827997 | B | Inhibitory concentration against Nicotinic acetylcholine receptor alpha-6-alpha-3-beta-2-beta-3; Range is 0.7-1 nM | Homo sapiens | 1 | ALA1145159 | protein complex format | Scientific Literature | |
2. | ALA2187460 | B | Displacement of [125I]epibatidine from human alpha6/alpha3beta2beta3 nAChR expressed in HEK293T cells | Homo sapiens | 7 | ALA2176949 | cell-based format | Scientific Literature | |
3. | ALA2412567 | B | Antagonist activity at human alpha6/alpha3beta2beta3 nAChR expressed in human SHEP1 cells assessed as inhibition of carbamylcholine-induced 86Rb+ ion efflux preincubated for 10 mins by liquid scintillation counting analysis relative to control | Homo sapiens | 5 | ALA2407064 | cell-based format | Scientific Literature | |
4. | ALA2412568 | B | Antagonist activity at human alpha6/alpha3beta2beta3 nAChR expressed in human SHEP1 cells assessed as inhibition of carbamylcholine-induced 86Rb+ ion efflux preincubated for 10 mins by liquid scintillation counting analysis | Homo sapiens | 5 | ALA2407064 | cell-based format | Scientific Literature | |
5. | ALA2412575 | B | Agonist activity at human alpha6/alpha3beta2beta3 nAChR expressed in human SHEP1 cells assessed as stimulation of 86Rb+ ion efflux after 5 mins by liquid scintillation counting analysis relative to carbamylcholine | Homo sapiens | 5 | ALA2407064 | cell-based format | Scientific Literature | |
6. | ALA2412576 | B | Agonist activity at human alpha6/alpha3beta2beta3 nAChR expressed in human SHEP1 cells assessed as stimulation of 86Rb+ ion efflux after 5 mins by liquid scintillation counting analysis | Homo sapiens | 5 | ALA2407064 | cell-based format | Scientific Literature | |
7. | ALA3107580 | B | Antagonist activity at human alpha6/alpha3beta2beta3 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiology method | Homo sapiens | 1 | ALA3102714 | cell-based format | Scientific Literature | |
8. | ALA3365056 | B | Displacement of [3H]epibatidine from human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells by liquid scintillation counting | Homo sapiens | 22 | ALA3352319 | cell-based format | Scientific Literature | |
9. | ALA3365061 | B | Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assay | Homo sapiens | 19 | ALA3352319 | cell-based format | Scientific Literature | |
10. | ALA3365062 | B | Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assay relative to control | Homo sapiens | 19 | ALA3352319 | cell-based format | Scientific Literature | |
11. | ALA4811727 | B | Inhibition of human alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Homo sapiens | 2 | ALA4811225 | cell-based format | Scientific Literature |