| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1763990 | Functional | Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current response at 100 nM by voltage clamp electrophysiology assay | 40 | ALA1759897 | assay format | Scientific Literature | ||
| 2. | ALA1763991 | Functional | Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assay | 8 | ALA1759897 | assay format | Scientific Literature | ||
| 3. | ALA4358818 | Binding | Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage clamp assay | Homo sapiens | 6 | ALA4354859 | cell-based format | Scientific Literature | |
| 4. | ALA4358820 | Binding | Reversible inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage clamp assay | Homo sapiens | 3 | ALA4354859 | cell-based format | Scientific Literature | |
| 5. | ALA4358822 | Binding | Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes expressing alpha9:alpha10 mRNA injection ratio of 1:3 assessed as inhibition of ACh-evoked currents by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA4354859 | cell-based format | Scientific Literature | |
| 6. | ALA4358830 | Binding | Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents at 100 nM by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA4354859 | cell-based format | Scientific Literature | |
| 7. | ALA4358831 | Binding | Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents at 1 uM by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA4354859 | cell-based format | Scientific Literature | |
| 8. | ALA2427311 | Binding | Inhibition of nicotinic acetylcholine receptor subunit alpha-9 alpha-10 (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current at 3 uM by two-electrode voltage clamp method | Homo sapiens | 2 | ALA2424574 | cell-based format | Scientific Literature | |
| 9. | ALA3106943 | Binding | Inhibition of alpha9alpha10 nAChR (unknown origin) expressed in Xenopus laevis oocytes at 1 uM by voltage clamp electrophysiology method | Homo sapiens | 1 | ALA3102714 | cell-based format | Scientific Literature | |
| 10. | ALA3107449 | Binding | Inhibition of alpha9alpha10 (unknown origin) nAChR | Homo sapiens | 1 | ALA3102714 | protein complex format | Scientific Literature | |
| 11. | ALA3107450 | Binding | Inhibition of human alpha9alpha10 nAChR | Homo sapiens | 1 | ALA3102714 | protein complex format | Scientific Literature | |
| 12. | ALA4224315 | Binding | Inhibition of human alpha9/alpha10 nACHR (1:1) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current measured for 2 to 5 days at -80 mV holding potential by two electrode voltage clamp method | Homo sapiens | 3 | ALA4219259 | assay format | Scientific Literature | |
| 13. | ALA4224316 | Binding | Inhibition of human alpha9/alpha10 nACHR (3:2) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current at 1 uM measured for 2 to 5 days at -80 mV holding potential by two electrode voltage clamp method | Homo sapiens | 1 | ALA4219259 | assay format | Scientific Literature | |
| 14. | ALA4224317 | Binding | Inhibition of human alpha9/alpha10 nACHR (4:1) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current at 1 uM measured for 2 to 5 days at -80 mV holding potential by two electrode voltage clamp method | Homo sapiens | 1 | ALA4219259 | assay format | Scientific Literature | |
| 15. | ALA4224318 | Binding | Inhibition of human alpha9/alpha10 nACHR (2:3) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current at 1 uM measured for 2 to 5 days at -80 mV holding potential by two electrode voltage clamp method | Homo sapiens | 1 | ALA4219259 | assay format | Scientific Literature | |
| 16. | ALA4224319 | Binding | Inhibition of human alpha9 N154G mutant/alpha10 nACHR (1:3) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current at 1 uM measured for 2 to 5 days at -80 mV holding potential by two electrode voltage clamp method | Homo sapiens | 1 | ALA4219259 | assay format | Scientific Literature | |
| 17. | ALA4224320 | Binding | Inhibition of human alpha9 N154G mutant/alpha10 nACHR (3:1) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current at 1 uM measured for 2 to 5 days at -80 mV holding potential by two electrode voltage clamp method | Homo sapiens | 1 | ALA4219259 | assay format | Scientific Literature | |
| 18. | ALA4224321 | Binding | Inhibition of human alpha9/alpha10 nACHR (1:3) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current measured for 2 to 5 days at -80 mV holding potential by two electrode voltage clamp method | Homo sapiens | 3 | ALA4219259 | assay format | Scientific Literature | |
| 19. | ALA4224322 | Binding | Inhibition of human alpha9/alpha10 nACHR (3:1) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current measured for 2 to 5 days at -80 mV holding potential by two electrode voltage clamp method | Homo sapiens | 3 | ALA4219259 | assay format | Scientific Literature | |
| 20. | ALA4224323 | Binding | Inhibition of human alpha9 N154G mutant/alpha10 nACHR (1:3) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current measured for 2 to 5 days at -80 mV holding potential by two electrode voltage clamp method | Homo sapiens | 3 | ALA4219259 | assay format | Scientific Literature |
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