| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2098496 | F | GSK_TB: Intracellular minimum inhibitory concentration (MIC) H37Rv assay | Mycobacterium tuberculosis H37Rv | 177 | organism-based format | GSK Tuberculosis Screening | ||
| 2. | ALA2187418 | A | Drug metabolism in Mycobacterium tuberculosis H37Rv assessed as tizoxanide formation at 1 to 10 fold MIC after 16 hrs by LC/MS analysis | Mycobacterium tuberculosis H37Rv | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2187801 | A | Potentiation of nitazoxanide drug uptake in Mycobacterium tuberculosis H37Rv at 0.5 mM after 16 hrs at pH 6.5 by LC/MS analysis in presence of acidified nitrite | Mycobacterium tuberculosis H37Rv | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA2187802 | A | Potentiation of nitazoxanide drug uptake in Mycobacterium tuberculosis H37Rv at 0.5 mM after 16 hrs at pH 5.5 by LC/MS analysis | Mycobacterium tuberculosis H37Rv | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA2187803 | A | Drug metabolism in Mycobacterium tuberculosis H37Rv assessed as [13C]acetylation at 1 to 10 fold MIC after 16 hrs by LC/MS analysis | Mycobacterium tuberculosis H37Rv | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA2187804 | A | Drug uptake in Mycobacterium tuberculosis H37Rv at 1 to 10 fold MIC after 16 hrs by LC/MS analysis | Mycobacterium tuberculosis H37Rv | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA3128596 | A | Drug metabolism in Mycobacterium tuberculosis H37Rv assessed as compound remaining at 0.25 to 5 times MIC for 16 hrs measured 15 to 60 mins post compound washout | Mycobacterium tuberculosis H37Rv | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA3615839 | A | Drug uptake in Mycobacterium tuberculosis H37Rv at 25 uM after 24 hrs by LC-MS/MS analysis | Mycobacterium tuberculosis H37Rv | 2 | organism-based format | Scientific Literature | ||
| 9. | ALA3637831 | F | GSK_TB: Minimum inhibitory concentration against H37Rv stain of Mycobacterium tuberculosis using MABA method | Mycobacterium tuberculosis H37Rv | 50 | organism-based format | GSK Tuberculosis Screening | ||
| 10. | ALA3637833 | F | GSK_TB: Inhibition of the intracellular growth of Mycobacterium tuberculosis (pXC50) | Mycobacterium tuberculosis H37Rv | 47 | organism-based format | GSK Tuberculosis Screening | ||
| 11. | ALA3637834 | F | GSK_TB: Minimum inhibitory concentration against isoniazid and rifampicin resistant clinical isolates of Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv | 9 | organism-based format | GSK Tuberculosis Screening | ||
| 12. | ALA3637835 | F | GSK_TB: Activity against non-replicating Mycobacterium tuberculosis (% inhibition) | Mycobacterium tuberculosis H37Rv | 50 | organism-based format | GSK Tuberculosis Screening | ||
| 13. | ALA3637836 | F | GSK_TB: Growth inhibition of non-replicating Mycobacterium tuberculosis (pXC50) | Mycobacterium tuberculosis H37Rv | 5 | organism-based format | GSK Tuberculosis Screening | ||
| 14. | ALA5056378 | F | Antitubercular activity against rifampicin resistant Mycobacterium tuberculosis H37Rv harboring RpoBS522L mutant assessed as bacterial growth inhibition measured after 5 days by serial dilution method | Mycobacterium tuberculosis | 11 | organism-based format | Scientific Literature | ||
| 15. | ALA5057945 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv assessed as reduction in bacterial growth incubated for 5 days by resazurin assay | Mycobacterium tuberculosis | 19 | organism-based format | Scientific Literature | ||
| 16. | ALA5057946 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv infected in human THP-1 macrophages assessed as reduction in microbial growth incubated for 72 hrs | Mycobacterium tuberculosis | 14 | organism-based format | Scientific Literature | ||
| 17. | ALA5113640 | F | Antibacterial activity against Mycobacterium tuberculosis H37Rv expressing GFP incubated for 7 days | Mycobacterium tuberculosis variant bovis | 16 | organism-based format | Scientific Literature | ||
| 18. | ALA5113641 | F | Antibacterial activity against Mycobacterium tuberculosis H37Rv expressing GFP infected in mouse Raw264.7 cells incubated for 5 days by SYTO 60 staining method | Mycobacterium tuberculosis variant bovis | 16 | organism-based format | Scientific Literature |
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