#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA676110	B	Selectivity for endothelin A receptor over endothelin receptor B	Rattus norvegicus	9	ALA1148449	protein format	Scientific Literature
2.	ALA675445	B	Binding affinity against Endothelin receptor from rat heart ventricle		30	ALA1127071	protein format	Scientific Literature
3.	ALA675446	B	Inhibition constant for the displacement of specific binding of [125I]-ET (Kd=2 nM) bound to rat pituitary membrane	Rattus norvegicus	3	ALA1133454	tissue-based format	Scientific Literature
4.	ALA675447	B	Inhibition constant for the displacement of specific binding of [125I]-ET (Kd=2 nM) bound to rat pituitary membrane; No significant binding at 10 uM	Rattus norvegicus	3	ALA1133454	tissue-based format	Scientific Literature
5.	ALA675448	B	Inhibition constant for the displacement of specific binding of [125I]-ET (Kd=2 nM) bound to rat pituitary membrane; Not tested	Rattus norvegicus	1	ALA1133454	tissue-based format	Scientific Literature
6.	ALA710602	F	Inhibition of phosphoinositol hydrolysis of MMQ cells.	Homo sapiens	21	ALA1129506	cell-based format	Scientific Literature
7.	ALA773106	F	Compound was tested for %reduction of big ET-induced blood pressure increase in drug treated rats with LU 135252 and balanced ETA/B receptor antagonists at 10 mg/kg oral dose, 2 hr pretreatment	Rattus norvegicus	1	ALA1132335	organism-based format	Scientific Literature
8.	ALA773107	F	Compound was tested for inhibition of big ET-induced blood pressure increase in drug treated rats with LU 135252 and balanced ETA/B receptor antagonists at 10 mg/kg oral dose, 2 hr pretreatment	Rattus norvegicus	1	ALA1132335	organism-based format	Scientific Literature
9.	ALA879064	F	Inhibitory potency at native endothelin A and endothelin B receptors by inhibiting endothelin-1 contractions of rat aortic rings	Homo sapiens	27	ALA1149183	assay format	Scientific Literature
10.	ALA796076	F	Inhibitory potency at native endothelin A and endothelin B receptors by inhibiting endothelin-1 contractions of rat aortic rings	Homo sapiens	48	ALA1149183	assay format	Scientific Literature
11.	ALA796077	F	Inhibitory potency at native endothelin A and B receptors by inhibiting sarafotoxin Sf6 contractions of rat tracheal rings	Rattus norvegicus	9	ALA1149183	assay format	Scientific Literature
12.	ALA845845	F	In vivo prevention of ET-1-induced sudden death in 5 rats by pretreatment with endothelin receptor antagonist at a dose of 100 mg/kg p.o.; 0/5	Rattus norvegicus	2	ALA1129322	organism-based format	Scientific Literature
13.	ALA846846	F	In vivo prevention of ET-1-induced sudden death in 5 rats by pretreatment with endothelin receptor antagonist at a dose of 10 mg/kg p.o.; 5/5	Rattus norvegicus	1	ALA1129322	organism-based format	Scientific Literature
14.	ALA846847	F	In vivo prevention of ET-1-induced sudden death in 6 rats by pretreatment with endothelin receptor antagonist at a dose of 10 mg/kg p.o.; 6/6	Rattus norvegicus	1	ALA1129322	organism-based format	Scientific Literature
15.	ALA846848	F	In vivo prevention of ET-1-induced sudden death in 6 rats by pretreatment with endothelin receptor antagonist at a dose of 30 mg/kg p.o.	Rattus norvegicus	1	ALA1129322	organism-based format	Scientific Literature
16.	ALA846849	F	In vivo prevention of ET-1-induced sudden death in 6 rats by pretreatment with endothelin receptor antagonist at a dose of 30 mg/kg p.o.; 0/6	Rattus norvegicus	1	ALA1129322	organism-based format	Scientific Literature
17.	ALA846850	F	In vivo prevention of ET-1-induced sudden death in 6 rats by pretreatment with endothelin receptor antagonist at a dose of 30 mg/kg p.o.; 2/6	Rattus norvegicus	1	ALA1129322	organism-based format	Scientific Literature
18.	ALA846851	F	In vivo prevention of ET-1-induced sudden death in 9 rats by pretreatment with endothelin receptor antagonist at a dose of 30 mg/kg p.o.; 9/9	Rattus norvegicus	1	ALA1129322	organism-based format	Scientific Literature
19.	ALA846852	F	In vivo prevention of ET-1-induced sudden death in rats by pretreatment with endothelin receptor antagonist at a dose of 100 mg/kg p.o.; nd = not determined	Rattus norvegicus	3	ALA1129322	organism-based format	Scientific Literature
20.	ALA846853	F	In vivo prevention of ET-1-induced sudden death in rats by pretreatment with endothelin receptor antagonist at a dose of 10 mg/kg p.o.; nd = not determined	Rattus norvegicus	3	ALA1129322	organism-based format	Scientific Literature