| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA797541 | B | Inhibition of ROKa in presence of 10 uM ATP | Homo sapiens | 1 | protein format | Scientific Literature | ||
| 2. | ALA804973 | B | Inhibition of ROKa in presence of 10 uM ATP | Homo sapiens | 2 | protein format | Scientific Literature | ||
| 3. | ALA805130 | B | Inhibition of ROKa in presence of 10 uM ATP | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
| 4. | ALA835975 | B | Percent control of rho kinase activity at 10 uM in the presence of 100 uM ATP | 5 | protein format | Scientific Literature | |||
| 5. | ALA918244 | B | Inhibition of Rho kinase | Homo sapiens | 51 | protein complex format | Scientific Literature | ||
| 6. | ALA915970 | B | Inhibition of Rho kinase | Homo sapiens | 24 | protein complex format | Scientific Literature | ||
| 7. | ALA915977 | F | Inhibition of TPA-induced Rho kinase dependent MBS phosphorylation in MDCK 2 cells | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3405453 | B | Inhibition of ROCK (unknown origin) | Homo sapiens | 16 | protein complex format | Scientific Literature | ||
| 9. | ALA4261137 | B | Inhibition of ROCK in human Hela cells assessed as reduction in cell spreading at 2 uM by phalloidin-based immunofluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4261165 | B | Inhibition of ROCK in human Hela cells assessed as formation of long neurite-like extensions at 2 uM by phalloidin-based immunofluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4261166 | B | Inhibition of ROCK in human Hela cells assessed as reduction in focal contact at 2 uM by phalloidin-based immunofluorescence assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA4328676 | B | Inhibition of ROCK1/2 in human PANC1 cells assessed as reduction in MYPT1 phosphorylation after 1 hr by ELISA | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 13. | ALA4361952 | B | Inhibition of ROCK (unknown origin) | Homo sapiens | 1 | protein format | Scientific Literature | ||
| 14. | ALA4378287 | B | Inhibition of human ROCK incubated for 20 mins followed by 33P ATP after 120 mins | Homo sapiens | 2 | protein format | Scientific Literature | ||
| 15. | ALA4379106 | B | Inhibition of ROCK in human SH-SY5Y cells assessed as decrease in phosphorylated MYPT1 level measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4379107 | B | Inhibition of ROCK in human SH-SY5Y cells assessed as decrease in phosphorylated MYPT1 level at 10 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4399589 | B | Inhibition of ROCK (unknown origin) using Myelin Basic Protein as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid scintillation counter | Homo sapiens | 3 | protein format | Scientific Literature | ||
| 18. | ALA4417742 | B | Inhibition of ROCK mediated signaling (unknown origin) assessed as reduction in G-protein-activated luciferase expression at 10 to 50 uM by SRE-luciferase expression based assay | Homo sapiens | 1 | assay format | Patent Bioactivity Data |
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