| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA808442 | B | Relative binding affinity for nuclear receptor from rat liver compared to thyroxine (T4) as KA(comp)/KA(T4 | 11 | ALA1123874 | assay format | Scientific Literature | ||
| 2. | ALA845320 | B | Selectivity measured as ratio of TRalpha Ki/TRbeta Ki | 19 | ALA1136512 | protein complex format | Scientific Literature | ||
| 3. | ALA851258 | B | Ratio of chronic administration on TRAF alpha-1 receptor to that of chronic administration on TRAF beta-1 receptor was determined | Homo sapiens | 4 | ALA1136772 | protein complex format | Scientific Literature | |
| 4. | ALA852812 | B | Ratio of concentration required to inhibit 50% of I-T3 binding to hTR-alpha1 to that of concentration required to inhibit 50% of I-T3 binding to hTR-beta1 was determined | Homo sapiens | 10 | ALA1136772 | protein complex format | Scientific Literature | |
| 5. | ALA840700 | B | Selectivity of compound was determined against thyroid hormone receptor | 1 | ALA1145987 | protein complex format | Scientific Literature | ||
| 6. | ALA840701 | B | Selectivity of compound was determined against thyroid hormone receptor | 5 | ALA1145987 | protein complex format | Scientific Literature | ||
| 7. | ALA875213 | B | Binding affinity for human Thyroid hormone receptor | Homo sapiens | 1 | ALA1143623 | protein complex format | Scientific Literature | |
| 8. | ALA839764 | F | Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells | Homo sapiens | 2 | ALA1143500 | cell-based format | Scientific Literature | |
| 9. | ALA829011 | F | Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells | Homo sapiens | 18 | ALA1143500 | cell-based format | Scientific Literature | |
| 10. | ALA829648 | B | Selectivity for THRalpha and THRbeta, ratio of EC50 | Homo sapiens | 4 | ALA1143500 | protein complex format | Scientific Literature | |
| 11. | ALA829757 | F | Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells | Homo sapiens | 1 | ALA1143500 | cell-based format | Scientific Literature | |
| 12. | ALA884148 | B | Ratio of IC50 of thyroid hormone receptor alpha 1 to that of thyroid hormone receptor beta 1 | Homo sapiens | 14 | ALA1142857 | protein complex format | Scientific Literature | |
| 13. | ALA859495 | B | Percentage binding to thyroid hormone receptor at 10 uM | 1 | ALA1147762 | protein complex format | Scientific Literature | ||
| 14. | ALA867120 | B | Selectivity for human thyroid hormone receptor beta 1 over thyroid hormone receptor alpha 1 | Homo sapiens | 6 | ALA1149453 | protein complex format | Scientific Literature | |
| 15. | ALA865294 | B | Binding affinity to thyroid hormone receptor at 10 uM | 1 | ALA1138125 | protein complex format | Scientific Literature | ||
| 16. | ALA866543 | B | Selectivity ratio of human TR-alpha-1 over TRbeta1 | Homo sapiens | 8 | ALA1138993 | protein complex format | Scientific Literature | |
| 17. | ALA907130 | B | Selectivity for human TR-alpha-1 over TRbeta1 | Homo sapiens | 3 | ALA1137319 | protein complex format | Scientific Literature | |
| 18. | ALA887906 | F | Agonist activity at THR in HepG2 cells by whole cell assay | Homo sapiens | 12 | ALA1139981 | cell-based format | Scientific Literature | |
| 19. | ALA926597 | B | Displacement of [3H]triiodothyronine from human thyroid hormone receptor at 10 uM | Homo sapiens | 13 | ALA1140711 | protein complex format | Scientific Literature | |
| 20. | ALA1068517 | B | Binding affinity to thyroid hormone receptor in human HepG2 cells | Homo sapiens | 1 | ALA1153106 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!