# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA831654 | Binding | Calculated inhibitory concentration against Peroxisome proliferator activated receptor dual model as sum of pIC50s for PPARalpha and PPARgamma | 34 | ALA1143611 | protein format | Scientific Literature | ||
2. | ALA831952 | Binding | Intrinsic activity against Peroxisome proliferator activated receptors at 1 uM relative to 1 uM GW-2331 for PPARalpha or rosiglitazone for PPARgamma | Homo sapiens | 4 | ALA1143556 | protein format | Scientific Literature | |
3. | ALA868633 | Binding | Ratio for binding affinity to PPARalpha over PPARgamma | Homo sapiens | 23 | ALA1146855 | protein format | Scientific Literature | |
4. | ALA910801 | Binding | Selectivity for human PPARgamma over human PPARalpha | Homo sapiens | 2 | ALA1146164 | protein format | Scientific Literature | |
5. | ALA3399723 | Binding | Agonist activity at PPARalpha/PPARgamma in human HepaR cells assessed as increase in HMGCS2 gene expression at 25 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 1 | ALA3396953 | cell-based format | Scientific Literature | |
6. | ALA3399724 | Binding | Agonist activity at PPARalpha/PPARgamma in human HepaR cells assessed as increase in CPT1A gene expression at 25 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 1 | ALA3396953 | cell-based format | Scientific Literature | |
7. | ALA3399725 | Binding | Agonist activity at PPARalpha/PPARgamma in human HepaR cells assessed as increase in CD36 gene expression at 25 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 1 | ALA3396953 | cell-based format | Scientific Literature | |
8. | ALA3399726 | Binding | Agonist activity at PPARalpha/PPARgamma in human HepaR cells assessed as increase in ANGPTL4 gene expression at 25 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 1 | ALA3396953 | cell-based format | Scientific Literature | |
9. | ALA3399727 | Binding | Agonist activity at PPARalpha/PPARgamma in human HepaR cells assessed as increase in FABP4 gene expression at 25 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 1 | ALA3396953 | cell-based format | Scientific Literature | |
10. | ALA3399728 | Binding | Agonist activity at PPARalpha/PPARgamma in human HepaR cells assessed as increase in FABP1 gene expression at 25 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 1 | ALA3396953 | cell-based format | Scientific Literature | |
11. | ALA3399729 | Binding | Agonist activity at PPARalpha/PPARgamma in human HepaR cells assessed as increase in CPT1A gene expression at 10 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 1 | ALA3396953 | cell-based format | Scientific Literature | |
12. | ALA3399730 | Binding | Agonist activity at PPARalpha/PPARgamma in human HepaR cells assessed as increase in CD36 gene expression at 10 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 1 | ALA3396953 | cell-based format | Scientific Literature | |
13. | ALA3399731 | Binding | Agonist activity at PPARalpha/PPARgamma in human HepaR cells assessed as increase in ANGPTL4 gene expression at 10 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 1 | ALA3396953 | cell-based format | Scientific Literature | |
14. | ALA3399732 | Binding | Agonist activity at PPARalpha/PPARgamma in human HepaR cells assessed as increase in FABP4 gene expression at 10 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 1 | ALA3396953 | cell-based format | Scientific Literature | |
15. | ALA3399733 | Binding | Agonist activity at PPARalpha/PPARgamma in human HepaR cells assessed as increase in FABP1 gene expression at 10 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 1 | ALA3396953 | cell-based format | Scientific Literature | |
16. | ALA3399734 | Binding | Agonist activity at PPARalpha/PPARgamma in human HepaR cells assessed as increase in HMGCS2 gene expression at 10 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 1 | ALA3396953 | cell-based format | Scientific Literature | |
17. | ALA764466 | Binding | Transcriptional activation activity on human I272F-mutant Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells | Homo sapiens | 1 | ALA1136221 | cell-based format | Scientific Literature | |
18. | ALA3077605 | Binding | Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay | Homo sapiens | 25 | ALA3046028 | cell-based format | Scientific Literature | |
19. | ALA4184538 | ADME | Modulatory activity at PPARalpha/PPARgamma in human primary muscle cells assessed as effect on AKR1B1 gene expression at EC50 measured after 24 hrs | Homo sapiens | 1 | ALA4184082 | cell-based format | Scientific Literature | |
20. | ALA4184539 | ADME | Modulatory activity at PPARalpha/PPARgamma in human primary muscle cells assessed as effect on ATP5I gene expression at EC50 measured after 24 hrs | Homo sapiens | 1 | ALA4184082 | cell-based format | Scientific Literature |