| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA651185 | B | Binding affinity for recombinant rat alpha-2-beta-2-gamma-2 GABA-A receptor subunits expressed in HEK293 cells | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA680297 | B | Binding affinity for recombinant rat GABA-A receptor alpha-2-beta-2-gamma-2 subunits expressed in HEK293 cells | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA829786 | B | Displacement of [3H]flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha-2-beta-2-gamma-2 expressed in HEK293 cells | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
| 4. | ALA861093 | B | Displacement of [3H]flumazenil from rat GABA-Aalpha2 receptor plus beta-2-gamma-2 in HEK293 cells | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA859939 | B | Inhibition of [3H]flumazenil binding to rat GABA-Aalpha2 receptor plus beta-2-gamma-2 at 10 uM in HEK293 cells | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA917144 | B | Displacement of [3H]flumazenil from rat GABAA alpha-2-beta-2-gamma-2 expressed in HEK293 cells | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 7. | ALA917145 | B | Displacement of [3H]flumazenil from rat GABAA alpha-2-beta-2-gamma-2 expressed in HEK293 cells at 10 uM | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA950412 | B | Displacement of [3H]flumazenil in rat GABAA alpha-2-beta-3-gamma-2 receptor expressed in HEK293 cells | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA979091 | F | Agonist activity at rat recombinant GABA alpha-2-beta-3-gamma-2 receptor expressed in HEK293 cells assessed as induction of current by whole cell patch-clamp technique | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA979926 | F | Antagonist activity at recombinant rat GABAA alpha-2-beta-3-gamma-2 receptor expressed in HEK293 cells assessed as inhibition of GABA-induced current at 1 mM by whole-cell patch-clamp technique | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA979933 | B | Intrinsic activity at recombinant rat GABAA alpha-2-beta-3-gamma-2 receptor expressed in HEK293 cells assessed as induction of current at 1 mM by whole-cell patch-clamp technique relative to GABA | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA979935 | F | Antagonist activity at recombinant rat GABAA alpha-2-beta-3-gamma-2 receptor expressed in HEK293 cells assessed as inhibition of GABA-induced current at 1 uM by whole-cell patch-clamp technique | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA970802 | F | Agonist activity at recombinant rat GABAA alpha-2-beta-3-gamma-2 receptor expressed in HEK293 cells assessed as potentiation of GABA-induced current at 1 mM by whole-cell patch-clamp technique | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA971724 | F | Agonist activity at rat recombinant GABAA alpha-2-beta-3-gamma-2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by whole cell patch-clamp technique | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA995049 | B | Inhibition of benzodiazepine binding site of rat GABAA alpha-2-beta-3-gamma-2 at 3.16 uM | Rattus norvegicus | 3 | protein complex format | Scientific Literature | ||
| 16. | ALA1111369 | F | Inverse agonist activity at rat GABA alpha-2-beta-3-gamma-2 receptor expressed in HEK293 cells by electrophysiology assay relative to GABA | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 17. | ALA2340574 | B | Agonist activity at rat GABAA alpha2beta3gamma2 receptor expressed in Xenopus oocytes assessed as stimulation of GABA-induced chloride current at 1 uM incubated 30 secs prior to GABA induction measured after 15 mins by two-electrode voltage clamp assay relative to control | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 18. | ALA2341045 | B | Agonist activity at rat GABAA alpha2beta3gamma2 receptor expressed in Xenopus oocytes assessed as stimulation of GABA-induced chloride current at 100 nM incubated 30 secs prior to GABA induction measured after 15 mins by two-electrode voltage clamp assay relative to control | Rattus norvegicus | 6 | cell-based format | Scientific Literature |
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