# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA669143 | B | In vitro binding affinity for D2/D3 receptors in rat striatal homogenates by [125I]NCQ298 displacement. | 22 | ALA1130429 | assay format | Scientific Literature | ||
2. | ALA670902 | B | Ratio of binding affinities of D2 receptor to D3 receptor | 26 | ALA1136084 | protein format | Scientific Literature | ||
3. | ALA846424 | B | Relative binding to Dopamine D2 long and D3 receptors (Ratio of Ki) | Rattus norvegicus | 13 | ALA1146691 | protein format | Scientific Literature | |
4. | ALA849439 | B | Binding affinity ratio of D2/D3 | Rattus norvegicus | 19 | ALA1134329 | protein format | Scientific Literature | |
5. | ALA847473 | B | Dopamine D2/D3 ratio of the compound | 36 | ALA1134687 | protein format | Scientific Literature | ||
6. | ALA832297 | F | Percent change in rat brain dopamine D2/D3 receptor binding after 1 mg/kg raclopride treatment | Rattus norvegicus | 1 | ALA1139546 | organism-based format | Scientific Literature | |
7. | ALA832438 | F | Percent change in rat brain dopamine D2/D3 receptor binding after 0.2 mg/kg raclopride treatment | Rattus norvegicus | 1 | ALA1139546 | organism-based format | Scientific Literature | |
8. | ALA875562 | F | Percent change in rat brain dopamine D2/D3 receptor binding after 0.01 mg/kg raclopride treatment | Rattus norvegicus | 1 | ALA1139546 | organism-based format | Scientific Literature | |
9. | ALA832439 | F | Percent change in rat brain dopamine D2/D3 receptor binding after 0.04 mg/kg raclopride treatment | Rattus norvegicus | 1 | ALA1139546 | organism-based format | Scientific Literature | |
10. | ALA975014 | B | Selectivity for rat dopamine D3 receptor over rat dopamine D2 receptor | Rattus norvegicus | 6 | ALA1157158 | assay format | Scientific Literature | |
11. | ALA2026137 | B | Selectivity ratio of Ki for dopamine D2 receptor in rat striatal membranes to Ki for rat recombinant dopamine D3 receptor | Rattus norvegicus | 9 | ALA2021900 | cell membrane format | Scientific Literature | |
12. | ALA2149722 | B | Selectivity ratio of Ki for dopamine D2 like receptor in rat brain homogenates to Ki for dopamine D3 receptor in rat brain homogenates | Rattus norvegicus | 42 | ALA2146442 | tissue-based format | Scientific Literature | |
13. | ALA3065145 | F | Agonist activity at Rattus norvegicus (rat) dopamine D2/D3 receptor transfected in african green monkey COS7 cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 10 min relative to control | Rattus norvegicus | 5 | ALA3046632 | cell-based format | Scientific Literature | |
14. | ALA3056231 | F | Agonist activity at Rattus norvegicus (rat) dopamine D2/D3 receptor transfected in african green monkey COS7 cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 10 min | Rattus norvegicus | 5 | ALA3046632 | cell-based format | Scientific Literature | |
15. | ALA3057565 | B | Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D3 trunk/D2 tail receptor transfected in african green monkey COS7 cells after 1 hr by beta scintillation counting | Rattus norvegicus | 14 | ALA3046632 | cell-based format | Scientific Literature | |
16. | ALA3057566 | B | Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D2 trunk/D3 tail receptor transfected in african green monkey COS7 cells after 1 hr by beta scintillation counting | Rattus norvegicus | 14 | ALA3046632 | cell-based format | Scientific Literature | |
17. | ALA3057571 | B | Binding affinity to Rattus norvegicus (rat) chimeric dopamine D3 trunk/D2 tail receptor transfected in african green monkey COS7 cells after 1 hr by beta scintillation counting | Rattus norvegicus | 1 | ALA3046632 | cell-based format | Scientific Literature | |
18. | ALA3057572 | B | Binding affinity to Rattus norvegicus (rat) chimeric dopamine D2 trunk/D3 tail receptor transfected in african green monkey COS7 cells after 1 hr by beta scintillation counting | Rattus norvegicus | 1 | ALA3046632 | cell-based format | Scientific Literature | |
19. | ALA2434790 | B | Selectivity ratio of Ki for rat dopamine D2 receptor to Ki for rat dopamine D3 receptor | Rattus norvegicus | 1 | ALA2429816 | assay format | Scientific Literature | |
20. | ALA3768232 | B | Selectivity ratio of Ki for rat brain dopamine D2 receptor to Ki for rat brain dopamine D3 receptor | Rattus norvegicus | 5 | ALA3763143 | assay format | Scientific Literature |