# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA655431 | Binding | In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasma | 6 | ALA1145913 | cell-free format | Scientific Literature | ||
2. | ALA655432 | Binding | In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasma; Not tested | 4 | ALA1145913 | cell-free format | Scientific Literature | ||
3. | ALA655433 | Binding | Compound was tested for its inhibitory activity against carboxypeptidase A (CPA) | 9 | ALA1132056 | single protein format | Scientific Literature | ||
4. | ALA1041001 | Binding | Inhibition of Carboxypeptidase A assessed as amount of Cl-CPL consumed by UV spectrometer | 6 | ALA1155339 | single protein format | Scientific Literature | ||
5. | ALA1027877 | Binding | Inhibition of carboxypeptidase A up to 20 ug/ml | 1 | ALA1151812 | single protein format | Scientific Literature | ||
6. | ALA1027878 | Binding | Inhibition of carboxypeptidase A | 1 | ALA1151812 | single protein format | Scientific Literature | ||
7. | ALA849834 | Binding | Inactivation potency of compound against carboxypeptidase A (CPA) | 2 | ALA1130784 | single protein format | Scientific Literature | ||
8. | ALA969981 | Binding | Inhibition of carboxypeptidase A | 5 | ALA1155591 | single protein format | Scientific Literature | ||
9. | ALA969982 | Binding | Inhibition of carboxypeptidase A at 10 ug/ml | 3 | ALA1155591 | single protein format | Scientific Literature | ||
10. | ALA928318 | Binding | Inhibition of human recombinant CpA by fluorescence assay | Homo sapiens | 20 | ALA1141500 | single protein format | Scientific Literature | |
11. | ALA932068 | Binding | Inhibition of human recombinant carboxy peptidase A1 by fluorescence assay | Homo sapiens | 19 | ALA1142293 | single protein format | Scientific Literature | |
12. | ALA932478 | Binding | Inhibition of CPA | 6 | ALA1142385 | single protein format | Scientific Literature | ||
13. | ALA2439346 | Binding | Inhibition of carboxypeptidase A (unknown origin) at 43 uM after 30 mins | Homo sapiens | 1 | ALA2434955 | single protein format | Scientific Literature | |
14. | ALA3430190 | Binding | Inhibition of carboxypeptidase A (unknown origin) | Homo sapiens | 4 | ALA3425482 | single protein format | Scientific Literature | |
15. | ALA3580144 | Binding | Inhibition of CPA (unknown origin) | Homo sapiens | 4 | ALA3576790 | single protein format | Scientific Literature | |
16. | ALA3755112 | ADME | Stability of the compound in Tris buffer assessed as carboxypeptidase A (unknown origin)-mediated compound degradation at pH 7.5 at 37 degC after 4 hrs by UPLC analysis | Homo sapiens | 2 | ALA3751758 | single protein format | Scientific Literature | |
17. | ALA3755120 | ADME | Stability of the compound in Tris buffer assessed as carboxypeptidase A (unknown origin)-mediated compound degradation by measuring intact compound level at pH 7.5 at 37 degC after 6 hrs by UPLC analysis | Homo sapiens | 1 | ALA3751758 | single protein format | Scientific Literature | |
18. | ALA4140928 | Binding | Irreversible inhibition of recombinant human carboxypeptidase A1 expressed in Pichia pastoris using N-(4-methoxyphenylazoformyl)-Phe-OH as substrate measured for 600 secs by double reciprocal plot analysis | Homo sapiens | 6 | ALA4138140 | assay format | Scientific Literature | |
19. | ALA4413958 | Binding | Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotometry | Homo sapiens | 11 | ALA4411328 | single protein format | Scientific Literature | |
20. | ALA4413962 | Binding | Inhibition of human CPA1 using AAFP as substrate assessed as dissociation rate constant measured at pre-steady state by spectrophotometry | Homo sapiens | 4 | ALA4411328 | single protein format | Scientific Literature |