| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA822800 | F | Direct activation of chloride current in Xenopus laevis oocytes expressing human alpha-1-beta-1-gamma-2 GABA-A receptor subunits | Homo sapiens | 5 | ALA1131230 | cell-based format | Scientific Literature | |
| 2. | ALA821856 | F | Modulation of GABA-induced chloride currents in Xenopus laevis oocytes expressing human alpha-1-beta-1-gamma-2 GABA-A receptor subunits | Homo sapiens | 5 | ALA1131230 | cell-based format | Scientific Literature | |
| 3. | ALA821857 | F | Direct activation of chloride currents (percentage of 10 mM GABA response) in Xenopus laevis oocytes expressing human alpha-1-beta-1-gamma-2 GABA-A receptor subunits | Homo sapiens | 5 | ALA1131230 | cell-based format | Scientific Literature | |
| 4. | ALA822939 | F | Modulation of GABA-induced chloride currents (percentage of GABA EC20 response) against human alpha-1-beta-1-gamma-2 GABA-A receptor subunits expressed in Xenopus laevis oocytes | Homo sapiens | 5 | ALA1131230 | cell-based format | Scientific Literature | |
| 5. | ALA859635 | F | Efficacy against human GABA alpha-1 receptor expressed in mouse fibroblast L(tk-) cells by whole cell patch clamp method | Homo sapiens | 7 | ALA1149460 | cell-based format | Scientific Literature | |
| 6. | ALA861815 | B | Displacement of [3H]Flumazenil from human GABA-Aalpha1 receptor plus beta-2-gamma-2 expressed in HEK293 cells | Homo sapiens | 5 | ALA1146066 | cell-based format | Scientific Literature | |
| 7. | ALA888754 | B | Activity at human GABAA alpha-1-beta-2-gamma-2L expressed in Xenopus oocytes assessed as potentiation of GABA currents | Homo sapiens | 1 | ALA1145429 | cell-based format | Scientific Literature | |
| 8. | ALA888755 | B | Activity at human GABAA alpha-1-beta-2-gamma-2L expressed in Xenopus oocytes assessed as potentiation of GABA currents relative to GABA | Homo sapiens | 1 | ALA1145429 | cell-based format | Scientific Literature | |
| 9. | ALA894099 | F | Agonist activity at GABA alpha-1-beta-2-gamma-2 receptor expressed in HEK293 cells by Whole-cell patch-clamp technique | Homo sapiens | 3 | ALA1148721 | cell-based format | Scientific Literature | |
| 10. | ALA894100 | F | Agonist activity at GABA alpha-1-beta-2-gamma-2 receptor expressed in HEK293 cells by Whole-cell patch-clamp technique relative to GABA | Homo sapiens | 2 | ALA1148721 | cell-based format | Scientific Literature | |
| 11. | ALA886415 | F | Antagonist activity at GABAA alpha-1-beta-2-gamma-2 receptor expressed in Xenopus laevis oocytes assessed as reduction of GABA-induced chloride ion currents at 400 uM | Homo sapiens | 1 | ALA1139960 | cell-based format | Scientific Literature | |
| 12. | ALA924988 | B | Binding affinity to GABA alpha-1-beta-1-gamma-2 receptor | 1 | ALA1140697 | protein complex format | Scientific Literature | ||
| 13. | ALA2173482 | B | Modulation of human recombinant GABA-A alpha1beta1gamma2L receptor expressed in Xenopus laevis oocytes assessed as effect on GABA-induced chloride current at 0.01 uM incubated 60 seconds before addition of GABA measured after 30 seconds at holding potential -70 mV by two-microelectrode voltage clamp technique relative to control | Homo sapiens | 4 | ALA2169854 | cell-based format | Scientific Literature | |
| 14. | ALA2173483 | B | Modulation of human recombinant GABA-A alpha1beta1gamma2L receptor expressed in Xenopus laevis oocytes assessed as effect on GABA-induced chloride current at 0.1 uM incubated 60 seconds before addition of GABA measured after 30 seconds at holding potential -70 mV by two-microelectrode voltage clamp technique relative to control | Homo sapiens | 4 | ALA2169854 | cell-based format | Scientific Literature | |
| 15. | ALA2173484 | B | Modulation of human recombinant GABA-A alpha1beta1gamma2L receptor expressed in Xenopus laevis oocytes assessed as effect on GABA-induced chloride current at 1 uM incubated 60 seconds before addition of GABA measured after 30 seconds at holding potential -70 mV by two-microelectrode voltage clamp technique relative to control | Homo sapiens | 4 | ALA2169854 | cell-based format | Scientific Literature | |
| 16. | ALA2173485 | B | Modulation of human recombinant GABA-A alpha1beta1gamma2L receptor expressed in Xenopus laevis oocytes assessed as effect on GABA-induced chloride current at 10 uM incubated 60 seconds before addition of GABA measured after 30 seconds at holding potential -70 mV by two-microelectrode voltage clamp technique relative to control | Homo sapiens | 4 | ALA2169854 | cell-based format | Scientific Literature | |
| 17. | ALA2173573 | F | Antagonist at human recombinant GABA-A alpha1beta1gamma2L receptor expressed in Xenopus laevis oocytes assessed as blockade of diazepam-induced potentiation of GABA-induced chloride current at 10 uM incubated 60 seconds before addition of GABA measured after 30 seconds at holding potential -70 mV by two-microelectrode voltage clamp technique | Homo sapiens | 4 | ALA2169854 | cell-based format | Scientific Literature | |
| 18. | ALA3073010 | B | Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA alpha1beta1gamma2 receptor | Homo sapiens | 3 | ALA3045560 | protein complex format | Scientific Literature | |
| 19. | ALA4219573 | B | Agonist activity at recombinant human GABAA receptor alpha1beta1gamma2L expressed in Xenopus laevis oocytes incubated for 30 secs by electrophysiological method | Homo sapiens | 1 | ALA4219030 | cell-based format | Scientific Literature | |
| 20. | ALA4310250 | A | Positive allosteric modulation of GABA-A alpha1beta1gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GABA-induced chloride current after 15 mins at -70 mV holding potential by two-microelectrode voltage clamp method | Homo sapiens | 5 | ALA4308853 | cell-based format | Scientific Literature |
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