# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1943802 | B | Inhibition of Erk1/2 activation in rat C6 cells at 5 ug/ml after 15 mins by flow cytometric analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
2. | ALA1943803 | B | Inhibition of Erk1/2 activation in rat C6 cells at 5 ug/ml after 30 mins by flow cytometric analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
3. | ALA1943804 | B | Inhibition of Erk1/2 activation in rat C6 cells at 30 uM after 15 mins by flow cytometric analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
4. | ALA1943805 | B | Inhibition of Erk1/2 activation in rat C6 cells at 30 uM after 30 mins by flow cytometric analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
5. | ALA2015239 | B | Inhibition of NGF-induced ERK1/2 phosphorylation in rat PC12 cells at 1 uM after 15 mins by Western blotting analysis relative to beta-actin level (Rvb = 0.275 +/- 0.005) | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
6. | ALA2015240 | B | Inhibition of NGF-induced ERK1/2 phosphorylation in rat PC12 cells at 10 uM after 15 mins by Western blotting analysis relative to beta-actin level (Rvb = 0.275 +/- 0.005) | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
7. | ALA2015241 | B | Inhibition of NGF-induced ERK1/2 phosphorylation in rat PC12 cells at 50 uM after 15 mins by Western blotting analysis relative to beta-actin level (Rvb = 0.275 +/- 0.005) | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
8. | ALA2015242 | B | Inhibition of NGF-induced ERK1/2 phosphorylation in rat PC12 cells after 15 mins by Western blotting analysis relative to beta-actin level | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
9. | ALA978211 | B | Inhibition of ERK1/2 phosphorylation in antigen-stimulated rat RBL-2H3 cells at 50 uM by Western blot analysis in presence of dinitrophenylated bovine serum albumin | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
10. | ALA1114691 | B | Increase in Erk1/2 phosphorylation in rat PC12 cells at 10 uM after 5 mins by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
11. | ALA1114692 | B | Increase in Erk1/2 phosphorylation in rat PC12 cells at 10 uM after 6 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
12. | ALA1769697 | B | Inhibition of ERK1/2 phosphorylation in PDGF-stimulated rat VSMC at 5 uM treated for 30 mins before 10 mins of cell stimulation by Western blot analysis | Rattus norvegicus | 1 | protein format | Scientific Literature | ||
13. | ALA3734588 | B | Inhibition of ERK in cultured rat retinal ganglion cells exposed to oxygen glucose deprivation condition for 3 hrs assessed as protection against TRPM7-mediated cell death at by propidium iodide uptake assay | Rattus norvegicus | 1 | assay format | Patent Bioactivity Data | ||
14. | ALA3778275 | B | Effect on ERK1/2 phosphorylation in rat C6 cells at 10 to 50 uM after 0.5 to 24 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
15. | ALA4035563 | B | Increase in ERK1/2 phosphorylation in rat PC12 cells after 2 hrs by immunoblotting method | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
16. | ALA4035567 | B | Increase in NGF-induced ERK1/2 phosphorylation in rat PC12 cells at 5 to 25 uM after 2 hrs by immunoblotting method | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
17. | ALA4687021 | B | Inhibition of TGF-beta induced ERK1/2 phosphorylation in rat NRK-49F cells at 20 to 40 uM pretreated with compound for 1 to 2 hrs followed by TGF-beta stimulation for 1 hr by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
18. | ALA4769268 | B | Inhibition of ERK1/2 phosphorylation in rat H9c2 cells at 0.5 to 1 uM by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
19. | ALA5236511 | B | Inhibition of doxorubicin-induced ERK1/2 activation in rat H9c2 cells assessed as reduction in ERK1/2 phosphorylation at 20 uM in presence of doxorubicin by immunoblot analysis | Rattus norvegicus | 5 | cell-based format | Scientific Literature |