| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA678742 | B | In vitro binding affinity for human GABA-A receptor alpha-4-beta-3-gamma-2 subunits expressed in L(tk-) cell membranes | Homo sapiens | 4 | ALA1146597 | cell-based format | Scientific Literature | |
| 2. | ALA678743 | B | In vitro binding affinity for human GABA-A receptor alpha-4-beta-3-gamma-2 subunits expressed in L(tk-) cell membranes | Homo sapiens | 3 | ALA1146597 | cell-based format | Scientific Literature | |
| 3. | ALA681093 | B | In vitro inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-4-beta-3-gamma-2 subunits expressed in L(tk-)cells | Homo sapiens | 2 | ALA1147626 | cell-based format | Scientific Literature | |
| 4. | ALA681094 | F | Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-4-beta-3-gamma-2 | Homo sapiens | 8 | ALA1134098 | assay format | Scientific Literature | |
| 5. | ALA681095 | F | Antagonistic potency against human Effective dose for agonist activity on human Gamma-aminobutyric acid A receptor alpha-4-beta-3-gamma-2 | 1 | ALA1134098 | assay format | Scientific Literature | ||
| 6. | ALA682901 | F | Antagonistic potency against human Effective dose for agonist activity on human Gamma-aminobutyric acid A receptor alpha-4-beta-3-gamma-2 | 2 | ALA1134098 | assay format | Scientific Literature | ||
| 7. | ALA682902 | F | Maximal response relative to Gamma-aminobutyric acid A against human Gamma-aminobutyric-acid A receptor alpha-4-beta-3-gamma-2 expressed in Xenopus oocytes | Homo sapiens | 8 | ALA1134098 | cell-based format | Scientific Literature | |
| 8. | ALA682903 | B | Inhibition of [3H]-Ro-15-1788 binding to human alpha-4-beta-3-gamma-2 GABA-A receptor expressed in L(tk-) cells | Homo sapiens | 1 | ALA1148356 | cell-based format | Scientific Literature | |
| 9. | ALA839938 | B | Binding affinity towards gamma-aminobutyric-acid GABA-A receptor alpha-4-beta-3-gamma-2 | 1 | ALA1138841 | protein complex format | Scientific Literature | ||
| 10. | ALA991892 | B | Binding affinity to GABAA alpha-4-beta-3-gamma-2 receptor | 3 | ALA1157475 | protein complex format | Scientific Literature | ||
| 11. | ALA992824 | B | Activity at GABAA alpha-4-beta-3-gamma-2 receptor expressed in Xenopus oocytes assessed as potentiation of GABA-induced chloride current at 1 uM | 2 | ALA1157475 | cell-based format | Scientific Literature | ||
| 12. | ALA992832 | B | Activity at alpha-4-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current at 1 uM by voltage clamp assay | 1 | ALA1157475 | cell-based format | Scientific Literature | ||
| 13. | ALA948523 | B | Activity at alpha-4-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay | 1 | ALA1157475 | cell-based format | Scientific Literature | ||
| 14. | ALA999412 | B | Displacement of [3H]flunitrazepam from human recombinant GABAA alpha-4-beta-3-gamma-2 receptor expressed in HEK293 cells | Homo sapiens | 8 | ALA1141720 | cell-based format | Scientific Literature | |
| 15. | ALA1247951 | F | Antagonist activity at recombinant alpha-4-beta-3-gamma-2S receptor expressed in HEK 293-T/17 cells assessed as GABA-induced current at 30 uM by whole-cell recording relative to control | 1 | ALA1240486 | cell-based format | Scientific Literature | ||
| 16. | ALA1273613 | F | Agonist activity at human recombinant GABAA alpha-4-beta-3-gamma-2 receptor expressed in Xenopus oocytes at 1 to 10 uM by patch clamp technique | Homo sapiens | 2 | ALA1268934 | cell-based format | Scientific Literature | |
| 17. | ALA1273618 | B | Displacement of [3H]flunitrazepam from human recombinant GABAA alpha-4-beta-3-gamma-2 receptor expressed in HEK cells by liquid scintillation counting | Homo sapiens | 36 | ALA1268934 | cell-based format | Scientific Literature | |
| 18. | ALA1282593 | B | Binding affinity to human recombinant GABA alpha-4-beta-3-gamma-2 receptor | Homo sapiens | 2 | ALA1275264 | protein complex format | Scientific Literature | |
| 19. | ALA3058329 | B | Displacement of [3H]-Ro 15-4513 from Homo sapiens (human) recombinant GABAA alpha4beta3gamma2 receptor expressed in Ltk- cells after 1 hr by liquid scintillation counting | Homo sapiens | 14 | ALA3045465 | cell-based format | Scientific Literature | |
| 20. | ALA3993047 | B | Activity at GABAA alpha4beta3gamma2 receptor (unknown origin) expressed in HEK293T cells assessed as potentiation of GABA-mediated increase in channel current under holding potential at -80 mV at 1 uM by patch clamp assay | Homo sapiens | 1 | ALA3992505 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!