| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2114737 | F | PubChem BioAssay. Dose response confirmation of uHTS inhibitor hits of SUMO1-mediated protein-protein interactions using a fluorescence polarization assay. (Class of assay: confirmatory) | Homo sapiens | 292 | assay format | PubChem BioAssays | ||
| 2. | ALA2114825 | F | PubChem BioAssay. Dose response confirmation of uHTS inhibitor hits of SUMO1-mediated protein-protein interactions using a fluorescence resonance energy transfer assay. (Class of assay: confirmatory) | Homo sapiens | 292 | assay format | PubChem BioAssays | ||
| 3. | ALA3582505 | B | Binding affinity to recombinant His-tagged human SUMO1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of interaction with biotinylated DAXX-SIM peptide after 1 hr by AlphaLISA method | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 4. | ALA3582506 | B | Binding affinity to recombinant His-tagged human SUMO1 expressed in Escherichia coli BL21 (DE3) measured over 120 secs by SPR analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 5. | ALA3582508 | B | Binding affinity to recombinant His-tagged human SUMO1 expressed in Escherichia coli BL21 (DE3) at 500 uM by NMR saturation-transfer difference analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA4150872 | B | Inhibition of recombinant human N-terminal His6-tagged SUMO1 expressed in Escherichia coli assessed as reduction in FL-AR peptide sumoylation measured after 90 mins by electrophoretic mobility shift assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 7. | ALA4731550 | B | Inhibition of SUMO1 (unknown origin) assessed as reduction in SUMOylated RanGAP1 level at 50 uM incubated for 60 mins by western blot analysis | Homo sapiens | 28 | single protein format | Scientific Literature | ||
| 8. | ALA4731551 | B | Inhibition of SUMO1 in human PC3 cells assessed as reduction in SUMOylation level at 10 to 20 uM measured after 24 hrs by western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA4731552 | B | Inhibition of SUMO1 in human MDA-MB-231 cells assessed as reduction in SUMOylation level at 10 uM measured after 24 hrs by western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 10. | ALA4731558 | B | Inhibition of SUMO1 (unknown origin) assessed as reduction in SUMOylated RanGAP1 level at 5 uM incubated for 60 mins by western blot analysis | Homo sapiens | 2 | single protein format | Scientific Literature |
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