| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2114933 | F | PubChem BioAssay. Secondary Assay for Selectivity of PDI Inhibitors (against ERp5) Measured in Biochemical System Using Plate Reader - 2137-04_Inhibitor_Dose_DryPowder_Activity. (Class of assay: confirmatory) | Homo sapiens | ⋯ | biochemical format | PubChem BioAssays | ||
| 2. | ALA3214998 | B | PubChem BioAssay. Secondary Assay for Selectivity of PDI Inhibitors (against ERp5) Measured in Biochemical System Using Plate Reader - 2137-04_Inhibitor_Dose_DryPowder_Activity_Set3. (Class of assay: confirmatory) | 4 | biochemical format | PubChem BioAssays | |||
| 3. | ALA3214858 | B | PubChem BioAssay. Turbidometric Biochemical Primary HTS to identify inhibitors of ERp5 Measured in Biochemical System Using Plate Reader - 7002-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) | 4 | biochemical format | PubChem BioAssays | |||
| 4. | ALA4257298 | B | Inhibition of ERP5 (unknown origin) assessed as reduction in enzyme-mediated bovine insulin aggregation after 30 mins by turbidimetric assay | Homo sapiens | 9 | single protein format | Patent Bioactivity Data | ||
| 5. | ALA4682781 | B | Inhibition of PDIA6 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 1 hr and measured by insulin reduction assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 6. | ALA5145311 | B | Binding affinity to PDIA6 in human DOHH-2 cells measured after 6 hrs by pull-down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5145321 | B | Binding affinity to PDIA6 in human MDA-MB-453 cells measured after 6 hrs by pull-down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5145338 | B | Binding affinity to PDIA6 in human DOHH-2 cells at 10 uM measured after 6 hrs in presence of 100 uM PES by pull-down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5145355 | B | Binding affinity to PDIA6 in human MDA-MB-453 cells at 10 uM measured after 6 hrs in presence of 100 uM PES by pull-down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5145372 | B | Binding affinity to PDIA6 in human DOHH-2 cells by MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5147887 | B | Inhibition of ERp5 (unknown origin) reductase activity assessed as inhibition of PDI/DTT-mediated cleavage of disulfide bond in insulin in the presence of DTT incubated for 40 mins by spectrophotometric analysis | Homo sapiens | 1 | single protein format | Scientific Literature |
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