# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA656597 | B | Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates. | 22 | ALA1131446 | tissue-based format | Scientific Literature | ||
2. | ALA656598 | B | Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates. | 22 | ALA1131446 | tissue-based format | Scientific Literature | ||
3. | ALA703977 | B | Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | 39 | ALA1130013 | assay format | Scientific Literature | ||
4. | ALA1121069 | F | Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current at 100 nM by FLIPR calcium 4 assay | Rattus norvegicus | 11 | ALA1158565 | cell-based format | Scientific Literature | |
5. | ALA1121070 | F | Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current at 1000 nM by FLIPR calcium 4 assay | Rattus norvegicus | 13 | ALA1158565 | cell-based format | Scientific Literature | |
6. | ALA1121071 | F | Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current at 10 nM by FLIPR calcium 4 assay | Rattus norvegicus | 2 | ALA1158565 | cell-based format | Scientific Literature | |
7. | ALA1121072 | F | Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current at 200 nM by FLIPR calcium 4 assay | Rattus norvegicus | 27 | ALA1158565 | cell-based format | Scientific Literature | |
8. | ALA1121073 | F | Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current at 500 nM by FLIPR calcium 4 assay | Rattus norvegicus | 1 | ALA1158565 | cell-based format | Scientific Literature | |
9. | ALA1121084 | F | Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Rattus norvegicus | 69 | ALA1158565 | cell-based format | Scientific Literature | |
10. | ALA2384388 | B | Antagonist activity at rat CaV1.3alpha1D transfected in HEK293 cells by FLIPR assay | Rattus norvegicus | 90 | ALA2380260 | cell-based format | Scientific Literature | |
11. | ALA2401503 | B | Antagonist activity at rat voltage-dependent L-type calcium channel Cav1.3alpha-1D expressed in HEK293 cells by FLIPR assay relative to isradipine | Rattus norvegicus | 1 | ALA2396637 | cell-based format | Scientific Literature | |
12. | ALA2401506 | B | Antagonist activity at rat voltage-dependent L-type calcium channel Cav1.3alpha-1D expressed in HEK293 cells assessed as inhibition of end barium current at 1 to 10 uM by whole-cell patch-clamp electrophysiology technique | Rattus norvegicus | 1 | ALA2396637 | cell-based format | Scientific Literature | |
13. | ALA2399366 | B | Antagonist activity at rat voltage-dependent L-type calcium channel Cav1.3alpha-1D expressed in HEK293 cells assessed as inhibition of peak barium current at 1 to 10 uM by whole-cell patch-clamp electrophysiology technique | Rattus norvegicus | 1 | ALA2396637 | cell-based format | Scientific Literature | |
14. | ALA2399369 | B | Antagonist activity at rat voltage-dependent L-type calcium channel Cav1.3alpha-1D expressed in HEK293 cells by FLIPR assay | Rattus norvegicus | 37 | ALA2396637 | cell-based format | Scientific Literature |