# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1226060 | B | Inhibition TLR3-mediated NO production in mouse RAW264.7 cells at 300 uM | Mus musculus | 1 | ALA1221358 | cell-based format | Scientific Literature | |
2. | ALA2150442 | B | Inhibition of TLR3 in poly(I:C)-stimulated mouse RAW264.7 cells at 0.6 uM after 24 hrs | Mus musculus | 1 | ALA2146360 | cell-based format | Scientific Literature | |
3. | ALA2209293 | B | Inhibition of TRIF recruitment to TLR3 in C57BL/6 mouse BMDM cells assessed as inhibition of pI:pC-induced p38 MAPK activity up to 90 mins | Mus musculus | 1 | ALA2203171 | cell-based format | Scientific Literature | |
4. | ALA2209296 | B | Inhibition of TRIF recruitment to TLR3 in C57BL/6 mouse BMDM cells assessed as inhibition of pI:pC-induced IkappaBalpha degradation up to 90 mins by Western blot analysis | Mus musculus | 3 | ALA2203171 | cell-based format | Scientific Literature | |
5. | ALA2209297 | B | Inhibition of TRIF recruitment to TLR3 in C57BL/6 mouse BMDM cells assessed as inhibition of pI:pC-induced IkappaBalpha phosphorylation up to 90 mins by Western blot analysis | Mus musculus | 3 | ALA2203171 | cell-based format | Scientific Literature | |
6. | ALA3881375 | B | Antagonist activity at TLR3 in mouse RAW264.7 cells assessed as inhibition of Poly(I:C)-induced receptor activation by measuring NO production at 3 uM after 24 hrs | Mus musculus | 1 | ALA3880440 | cell-based format | Patent Bioactivity Data | |
7. | ALA3881379 | B | Antagonist activity at TLR3 in mouse RAW264.7 cells assessed as inhibition of Poly(I:C)-induced receptor activation by measuring NO production at 0.5 uM after 24 hrs | Mus musculus | 1 | ALA3880440 | cell-based format | Patent Bioactivity Data | |
8. | ALA4235578 | B | Antagonist activity at TLR3 in mouse BMDM assessed as inhibition of poly I:C-stimulated TNFalpha production at 25 uM preincubated for 1 hr followed by poly I:C stimulation for 11 hrs by ELISA | Mus musculus | 2 | ALA4229513 | cell-based format | Scientific Literature |